FSH for the Treatment of Male Infertility

L Casarini, P Crépieux, E Reiter, C Lazzaretti… - International journal of …, 2020 - mdpi.com
Follicle-stimulating hormone (FSH) supports spermatogenesis acting via its receptor
(FSHR), which activates trophic effects in gonadal Sertoli cells. These pathways are targeted …

Prospects for FSH treatment of male infertility

M Simoni, G Brigante, V Rochira… - The Journal of …, 2020 - academic.oup.com
Context Despite the new opportunities provided by assisted reproductive technology (ART),
male infertility treatment is far from being optimized. One possibility, based on …

Pharmacogenetics of FSH action in the male

M Schubert, L Pérez Lanuza, J Gromoll - Frontiers in endocrinology, 2019 - frontiersin.org
Male infertility is a major contributor to couple infertility, however in most cases it remains
“idiopathic” and putative treatment regimens are lacking. This leads to a scenario in which …

FSHB −211 G>T is a major genetic modulator of reproductive physiology and health in childbearing age women

K Rull, M Grigorova, A Ehrenberg, P Vaas… - Human …, 2018 - academic.oup.com
STUDY QUESTION Are the genetic variants FSHB− 211 G> T (rs10835638), FSHR c. 2039
A> G (Asn680Ser, rs6166) and FSHR− 29 G> A (rs1394205) associated with serum FSH, LH …

Prediction model for testis histology in men with non-obstructive azoospermia: Evidence for a limited predictive role of serum follicle-stimulating hormone

E Caroppo, EM Colpi, G D'Amato, G Gazzano… - Journal of Assisted …, 2019 - Springer
Purpose The present prediction model was intended to verify whether serum FSH level
could be predictive of testis histology in patients with non-obstructive azoospermia (NOA) …

[HTML][HTML] Study on the relationship between sex hormone changes and erectile dysfunction in patients with chronic prostatitis/chronic pelvic pain syndrome

D Fan, W Mao, G Wang, H Shi, Z Wu… - Annals of Palliative …, 2021 - apm.amegroups.org
Background: To investigate the relationship between serum sex hormones and erectile
dysfunction (ED), changes in erectile function and sex hormones were studied in patients …

Follicle-Stimulating Hormone Treatment and Male Idiopathic Infertility: Effects on Sperm Parameters and Oxidative Stress Indices according to FSHR c. 2039 A/G and …

LM Mongioì, RA Condorelli, A Alamo… - Journal of Clinical …, 2020 - mdpi.com
Scientific evidence shows that the administration of follicle-stimulating hormone (FSH) to
infertile patients with normal serum FSH concentrations improves sperm parameters in …

FSHB and FSHR gene variants exert mild modulatory effect on reproductive hormone levels and testis size but not on semen quality: A study of 2020 men from the …

AK Bang, K Almstrup, L Nordkap, L Priskorn… - …, 2021 - Wiley Online Library
Background Spermatogenesis depends on stimulation by follicle‐stimulating hormone
(FSH) which binds to FSH receptors (FSHR) on testicular Sertoli cells. Three FSH‐related …

[HTML][HTML] Combined effects of the FSHR 2039 A/G and FSHR-29 G/A polymorphisms on male reproductive parameters

R Cannarella, N Musso, RA Condorelli… - The World Journal of …, 2021 - ncbi.nlm.nih.gov
Purpose The aim of this study was to evaluate the combined effect of FSHR 2039 A/G and
FSHR-29 G/A single nucleotide polymorphisms (SNPs) on the male reproductive function in …

The 2039 A/G FSH receptor gene polymorphism influences glucose metabolism in healthy men

R Cannarella, N Musso, RA Condorelli, M Musmeci… - Endocrine, 2020 - Springer
Objective To assess the role of c. 2039 A/G (p. Asp680Ser)(rs6166) and c.− 29 G/A
(rs1394205) follicle-stimulating hormone receptor (FSHR) gene single nucleotide …