Hemostatic biomaterials to halt non-compressible hemorrhage

S Jiang, S Liu, S Lau, J Li - Journal of Materials Chemistry B, 2022 - pubs.rsc.org
Non-compressible hemorrhage is an unmet clinical challenge, which occurs in inaccessible
sites in the body where compression cannot be applied to stop bleeding. Current treatments …

Autologous blood clots: a natural biomaterial for wound healing

DM Richter, JC Ku, KE Keckler, LR Burke… - Frontiers in …, 2023 - frontiersin.org
Repair after injury in mammalian tissue involves a complex cascade of events, with the
formation of local blood clots being essential for the initial phases of wound healing. As a …

Material properties of nonpregnant and pregnant human uterine layers

DM Fodera, SR Russell, JLL Jackson, S Fang… - Journal of the …, 2024 - Elsevier
The uterus has critical biomechanical functions in pregnancy and undergoes dramatic
material growth and remodeling from implantation to parturition. The intrinsic material …

[HTML][HTML] Adhesive and cohesive fracture of blood clots: Experiments and modeling

S Liu, A Bahmani, GP Sugerman, Z Yang… - Journal of the …, 2024 - Elsevier
Blood clots represent living materials composed of a polymer network and an abundance of
cells. They might fracture within the bulk material of the clot (cohesive fracture), at the …

Mechanical properties of clot made from human and bovine whole blood differ significantly

GP Sugerman, GN Bechtel, Z Malinowska… - Journal of the …, 2024 - Elsevier
Thromboembolism–that is, clot formation and the subsequent fragmentation of clot–is a
leading cause of death worldwide. Clots' mechanical properties are critical determinants of …

Clots reveal anomalous elastic behavior of fiber networks

A Zakharov, M Awan, A Gopinath, SJJ Lee… - Science …, 2024 - science.org
The adaptive mechanical properties of soft and fibrous biological materials are relevant to
their functionality. The emergence of the macroscopic response of these materials to …

How to measure fracture toughness of soft materials: a comparison of six different approaches using blood clot as a model material

MJ Lohr, GN Bechtel, B Dortdivanlioglu… - International Journal of …, 2025 - Springer
Soft materials are an important class of materials. They play critical roles both in nature, in
the form of soft tissues, and in industrial applications. Quantifying their mechanical …

[HTML][HTML] Fibrin clot fracture under cyclic fatigue and variable rate loading

S Liu, A Bahmani, F Ghezelbash, J Li - Acta Biomaterialia, 2024 - Elsevier
Fibrin clot is a vital class of fibrous materials, governing the mechanical response of blood
clots. Fracture behavior of fibrin clots under complex physiological load is relevant for …

Modeling liquid droplet impact on a micropillar-arrayed viscoelastic surface via mechanically averaged responses

Y Li, J Cheng - Engineering Applications of Computational Fluid …, 2023 - Taylor & Francis
Droplet impact on a substrate is an intriguing phenomenon that widely exists in our daily life
and a broad range of industrial processes. However, droplet impact dynamics on soft …

External Bleeding and Advanced Biomacromolecules for Hemostasis

S Fanaee, W Austin, M Filiaggi, V Adibnia - Biomacromolecules, 2024 - ACS Publications
Hemorrhage is a significant medical problem that has been an active area of research over
the past few decades. The human body has a complex response to bleeding that leads to …