The protease activated receptor 2-CCAAT/enhancer-binding protein beta-SerpinB3 axis inhibition as a novel strategy for the treatment of non-alcoholic steatohepatitis
G Villano, E Novo, C Turato, S Quarta, M Ruvoletto… - Molecular …, 2024 - Elsevier
Objective The serine protease inhibitor SerpinB3 has been described as critical mediator of
liver fibrosis and it has been recently proposed as an additional hepatokine involved in …
liver fibrosis and it has been recently proposed as an additional hepatokine involved in …
SerpinB3: A Multifaceted Player in Health and Disease–Review and Future Perspectives
S Cagnin, P Pontisso, A Martini - 2024 - preprints.org
SerpinB3, a member of the serine-protease inhibitor family, has emerged as a crucial player
in various physiological and pathological processes. Initially identified as an oncogenic …
in various physiological and pathological processes. Initially identified as an oncogenic …
Inhibition of Protease Activated Receptor-2 Activation in Parkinson's Disease
S Quarta, M Sandre, M Ruvoletto, M Campagnolo… - 2024 - preprints.org
In Parkinson's disease, neuroinflammation is a complex defense mechanism. Activated
microglia and Proteinase-activated receptor-2 (PAR2) are key points in the regulation of …
microglia and Proteinase-activated receptor-2 (PAR2) are key points in the regulation of …