Benzodiazepines in the management of seizures and status epilepticus: a review of routes of delivery, pharmacokinetics, efficacy, and tolerability

R Kienitz, L Kay, I Beuchat, S Gelhard… - CNS drugs, 2022 - Springer
Status epilepticus (SE) is an acute, life-threatening medical condition that requires
immediate, effective therapy. Therefore, the acute care of prolonged seizures and SE is a …

[HTML][HTML] Treatment of benzodiazepine-resistant status epilepticus: Systematic review and network meta-analyses

P Jain, S Aneja, J Cunningham, R Arya, S Sharma - Seizure, 2022 - Elsevier
Purpose Multiple interventions have been studied for benzodiazepine-resistant status
epilepticus (SE) in children and adults. This review aimed to summarize the available …

Prediction of long-term survival after status epilepticus using the ACD score

LE Roberg, O Monsson, SB Kristensen, SM Dahl… - JAMA …, 2022 - jamanetwork.com
Importance Early prediction of long-term mortality in status epilepticus is important given the
high fatality rate in the years after diagnosis. Objective To improve prognostication of long …

Trends and differences in status epilepticus treatment of children and adults over 10 years: A comparative study of medical records (2012–2021) from a University …

L Purwien, S Schubert-Bast, M Kieslich… - CNS drugs, 2023 - Springer
Abstract Background and Objectives Over the last decade, significant advancements have
been made in status epilepticus (SE) management, influenced by landmark trials such as …

Refractory status epilepticus: risk factors and analysis of intubation in the multicenter SENSE registry

I Beuchat, F Rosenow, C Kellinghaus, E Trinka… - Neurology, 2022 - AAN Enterprises
Background and Objectives Refractory status epilepticus (RSE) bears significant morbidity
and mortality. Therapy escalation and in some cases intubation are recommended. Most …

Clinical presentation of new onset refractory status epilepticus in children (the pSERG cohort)

C Sculier, C Barcia Aguilar, N Gaspard… - …, 2021 - Wiley Online Library
Objective We aimed to characterize the clinical profile and outcomes of new onset refractory
status epilepticus (NORSE) in children, and investigated the relationship between fever …

Staged treatment response in status epilepticus: Lessons from the SENSE registry

I Beuchat, J Novy, F Rosenow, C Kellinghaus… - …, 2024 - Wiley Online Library
Objectives Although in epilepsy patients the likelihood of becoming seizure‐free decreases
substantially with each unsuccessful treatment, to our knowledge this has been poorly …

Clinical characteristics and outcomes of patients with recurrent status epilepticus episodes

K Bauer, F Rosenow, S Knake, LM Willems… - … Research and Practice, 2023 - Springer
Background Multiple studies have focused on medical and pharmacological treatments and
outcome predictors of patients with status epilepticus (SE). However, a sufficient …

How much refractory is 'refractory status epilepticus'? A retrospective study of treatment strategies and clinical outcomes

S Lattanzi, G Giovannini, N Orlandi, F Brigo… - Journal of …, 2023 - Springer
Background and purpose This study aimed to evaluate whether differences in clinical
outcomes exist according to treatments received and seizure activity resolution in patients …

Mortality, disability, and prognostic factors of status epilepticus: a nationwide population-based retrospective cohort study

SA Choi, H Lee, K Kim, SM Park, HJ Moon, YS Koo… - Neurology, 2022 - AAN Enterprises
Background and Objectives The outcome of status epilepticus (SE) largely varies depending
on clinical characteristics. Risk stratification is necessary for tailoring the aggressiveness of …