Androgen receptor (AR) is a validated drug target for prostate cancer based on its role in
proliferation, survival, and metastases of prostate cancer cells. Unfortunately, despite recent …

Effective regulation of immune-cell activation is critical for ensuring that the immune
response, and inflammation generated for the purpose of pathogen elimination, are limited …

Colorectal cancer (CRC) is one of the most common malignancies worldwide. Metastasis is
a major cause of CRC recurrence and mortality. Several antibiotic drugs have been reported …

Intravenously administered radiolabeled peptides targeting somatostatin receptors are used
for the treatment of unresectable gastroenteropancreatic neuroendocrine tumors (GEP …

Background Globally, despite prostate cancer (PCa) representing second most prevalent
malignancy in male, the precise molecular mechanisms implicated in its pathogenesis …

Background We are committed to investigate miR-218-5 effects on the progression of
cervical cancer (CC) cell and find out the molecular mechanism. Methods GSE9750 was …

Melanoma is a malignant tumor of cutaneous melanocytes that is characterized by high
grade malignancy, rapid progression and high mortality. Thus far, its specific etiological …

Kinases are downstream modulators and effectors of several cellular signaling cascades
and play key roles in the development of neoplastic disease. In this study, we aimed to …

The acquisition of an invasive phenotype by epithelial cells occurs through a loss of cellular
adhesion and polarity, heralding a multistep process that leads to metastatic dissemination …

Thyroid cancer is the most common malignancy of the endocrine glands, and during last
couple of decades, its incidence has risen alarmingly, across the globe. Etiology of thyroid …