Development of a NanoBRET assay platform to detect intracellular ligands for the chemokine receptors CCR6 and CXCR1

ME Huber, SL Wurnig, AFA Moumbock, L Toy… - …, 2024 - Wiley Online Library
A conserved intracellular allosteric binding site (IABS) was recently identified at several G
protein‐coupled receptors (GPCRs). This target site allows the binding of allosteric …

N-substituted-dioxocyclobutenylamino-3-hydroxy-picolinamides useful as CCR6 inhibitors

BS Gerstenberger, AC Flick, DWS Kung… - US Patent …, 2023 - Google Patents
US11708360B2 - N-substituted-dioxocyclobutenylamino-3-hydroxy-picolinamides useful as
CCR6 inhibitors - Google Patents US11708360B2 - N-substituted-dioxocyclobutenylamino-3-hydroxy-picolinamides …