Hydrogels as functional components in artificial cell systems

ME Allen, JW Hindley, DK Baxani, O Ces… - Nature Reviews …, 2022 - nature.com
Recent years have seen substantial efforts aimed at constructing artificial cells from various
molecular components with the aim of mimicking the processes, behaviours and …

Causal roles of mitochondrial dynamics in longevity and healthy aging

A Sharma, HJ Smith, P Yao, WB Mair - EMBO reports, 2019 - embopress.org
Mitochondria are organized in the cell in the form of a dynamic, interconnected network.
Mitochondrial dynamics, regulated by mitochondrial fission, fusion, and trafficking, ensure …

Spatially and optically tailored 3D printing for highly miniaturized and integrated microfluidics

JL Sanchez Noriega, NA Chartrand, JC Valdoz… - Nature …, 2021 - nature.com
Traditional 3D printing based on Digital Light Processing Stereolithography (DLP-SL) is
unnecessarily limiting as applied to microfluidic device fabrication, especially for high …

A pH-driven transition of the cytoplasm from a fluid-to a solid-like state promotes entry into dormancy

MC Munder, D Midtvedt, T Franzmann, E Nuske, O Otto… - elife, 2016 - elifesciences.org
Cells can enter into a dormant state when faced with unfavorable conditions. However, how
cells enter into and recover from this state is still poorly understood. Here, we study …

A glucose-starvation response regulates the diffusion of macromolecules

RP Joyner, JH Tang, J Helenius, E Dultz, C Brune… - elife, 2016 - elifesciences.org
The organization and biophysical properties of the cytosol implicitly govern molecular
interactions within cells. However, little is known about mechanisms by which cells regulate …

Dual-modified nanoparticles overcome sequential absorption barriers for oral insulin delivery

Z Xi, E Ahmad, W Zhang, J Li, A Wang, N Wang… - Journal of Controlled …, 2022 - Elsevier
The efficacy of oral insulin drug delivery is seriously hampered by multiple gastrointestinal
barriers, especially transepithelial barriers, including apical endocytosis, lysosomal …

Sonoelastomics for breast tumor classification: a radiomics approach with clustering-based feature selection on sonoelastography

Q Zhang, Y Xiao, J Suo, J Shi, J Yu, Y Guo… - Ultrasound in Medicine …, 2017 - Elsevier
A radiomics approach to sonoelastography, called “sonoelastomics,” is proposed for
classification of benign and malignant breast tumors. From sonoelastograms of breast …

Electrodiffusion phenomena in neuroscience: a neglected companion

LP Savtchenko, MM Poo, DA Rusakov - Nature reviews Neuroscience, 2017 - nature.com
The emerging technological revolution in genetically encoded molecular sensors and super-
resolution imaging provides neuroscientists with a pass to the real-time nano-world. On this …

Molecular theory of weak polyelectrolyte gels: the role of pH and salt concentration

GS Longo, M Olvera de La Cruz, I Szleifer - Macromolecules, 2011 - ACS Publications
We develop a detailed molecular theory that describes the response of weak polyelectrolyte
gels to changes in both the pH and salt concentration, c, of the solution. This approach …

Enhanced transcription and translation in clay hydrogel and implications for early life evolution

D Yang, S Peng, MR Hartman… - Scientific Reports, 2013 - nature.com
In most contemporary life forms, the confinement of cell membranes provides localized
concentration and protection for biomolecules, leading to efficient biochemical reactions …