Highlights•The human microbiota plays a pivotal role in protection against Candida
infections.•Bacterial metabolites influence the virulence of fungi via diverse …

Most microbes have developed responses that protect them against stresses relevant to
their niches. Some that inhabit reasonably predictable environments have evolved …

Fungal keratitis (FK) is a severe infectious corneal disease. Since traditional eye drops
exhibit poor dissolution and high corneal toxicity, the efficacy of current treatments for FK …

Microbial species capable of co-existing with healthy individuals, such as the commensal
fungus Candida albicans, exploit multifarious strategies to evade our immune defenses …

The cell wall of human fungal pathogens plays critical roles as an architectural scaffold and
as a target and modulator of the host immune response. Although the cell wall of the …

Cullin-1-RING ubiquitin ligases (CRL1) or SCF1 (SKP1-CUL1-RBX1) E3 ubiquitin ligases
are the largest and most extensively investigated class of E3 ligases in mammals that …

One of the ubiquitous hospital-acquired infections is associated with Candida albicans
fungus. Usually, this commensal fungus causes no harm to its human host, as it lives …

Objective: To evaluate the antifungal activity of hydralazine hydrochloride alone and in
synergy with azoles against Candida spp. and the action mechanism. Methods: We used …

Candida auris, a multidrug-resistant human fungal pathogen, was first identified in 2009 in
Japan. Since then, systemic C. auris infections have now been reported in more than 50 …

Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most commonly
encountered bacteria found in healthcare clinics and has been ranked a priority 2 pathogen …