Epidemiology of HPV-associated oropharyngeal cancer

KB Pytynia, KR Dahlstrom, EM Sturgis - Oral oncology, 2014 - Elsevier
Squamous cell carcinoma of the oropharynx is increasing in incidence in epidemic
proportion. This site specific increase in incidence is due to an increase in human …

Clinical significance of head and neck squamous cell cancer biomarkers

H Polanska, M Raudenska, J Gumulec… - Oral oncology, 2014 - Elsevier
Head and neck tumors belong among the six leading causes of cancer death worldwide.
The predominant type of head and neck tumors consists of squamous cell carcinomas …

Meta analysis: HPV and p16 pattern determines survival in patients with HNSCC and identifies potential new biologic subtype

AE Albers, X Qian, AM Kaufmann, A Coordes - Scientific reports, 2017 - nature.com
Consistent discrepancies in the p16/HPV-positivity have been observed in head and neck
squamous cell carcinoma (HNSCC). It is therefore questionable, if all HPV+ and/or p16+ …

Vitamin D deficiency in head and neck cancer patients–prevalence, prognostic value and impact on immune function

F Bochen, B Balensiefer, S Körner, JT Bittenbring… - …, 2018 - Taylor & Francis
Vitamin D deficiency is frequently observed in human cancer patients and a prognostic
relevance could be shown for some entities. Additionally, it is known that vitamin D can …

[HTML][HTML] Prognostic value of HPV DNA status in cervical cancer before treatment: a systematic review and meta-analysis

P Li, Y Tan, LX Zhu, LN Zhou, P Zeng, Q Liu… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Background Human papillomavirus (HPV), has been recognized as an vital preliminary
event in the oncogenesis of cervical cancer. But the prognostic value is not well defined …

Effect of HPV on head and neck cancer patient survival, by region and tumor site: a comparison of 1362 cases across three continents

G D'Souza, D Anantharaman, T Gheit… - Oral oncology, 2016 - Elsevier
Objectives To explore whether HPV-related biomarkers predict oropharyngeal squamous
cell cancer (OPSCC) survival similarly across different global regions, and to explore their …

[HTML][HTML] Role of human papillomavirus in oropharyngeal squamous cell carcinoma: A review

RSR Woods, EM O'Regan, S Kennedy… - World Journal of …, 2014 - ncbi.nlm.nih.gov
Human papillomavirus (HPV) has been implicated in the pathogenesis of a subset of
oropharyngeal squamous cell carcinoma. As a result, traditional paradigms in relation to the …

Meta-analysis of survival in patients with HNSCC discriminates risk depending on combined HPV and p16 status

A Coordes, K Lenz, X Qian, M Lenarz… - European Archives of …, 2016 - Springer
Data indicate a better prognosis for human papillomavirus (HPV)-associated head and neck
squamous cell carcinoma (HNSCC). HPV and p16 detection are established markers for …

The role of human papillomavirus on the prognosis and treatment of oropharyngeal carcinoma

N Fung, F Faraji, H Kang, C Fakhry - Cancer and Metastasis Reviews, 2017 - Springer
Human papillomavirus positive oropharyngeal cancer (HPV-positive OPC) is a distinct
subtype of head and neck carcinoma (HNC) distinguished from HPV-negative HNC by its …

Developing and validating a multivariable prognostic-predictive classifier for treatment escalation of oropharyngeal squamous cell carcinoma: the PREDICTR-OPC …

H Mehanna, D Rapozo, SV von Zeidler… - Clinical Cancer …, 2024 - AACR
Purpose: While there are several prognostic classifiers, to date, there are no validated
predictive models that inform treatment selection for oropharyngeal squamous cell …