The search for novel treatment strategies for Streptococcus pneumoniae infections
F Cools, P Delputte, P Cos - FEMS Microbiology Reviews, 2021 - academic.oup.com
This review provides an overview of the most important novel treatment strategies against
Streptococcus pneumoniae infections published over the past 10 years. The pneumococcus …
Streptococcus pneumoniae infections published over the past 10 years. The pneumococcus …
Streptococcal peptides and their roles in host-microbe interactions
ER Wahlenmayer, DE Hammers - Frontiers in Cellular and Infection …, 2023 - frontiersin.org
The genus Streptococcus encompasses many bacterial species that are associated with
hosts, ranging from asymptomatic colonizers and commensals to pathogens with a …
hosts, ranging from asymptomatic colonizers and commensals to pathogens with a …
Airway metabolic profiling during Streptococcus pneumoniae infection identifies branched chain amino acids as signatures of upper airway colonisation
Streptococcus pneumoniae is a leading cause of community-acquired pneumonia and
bacteraemia and is capable of remarkable phenotypic plasticity, responding rapidly to …
bacteraemia and is capable of remarkable phenotypic plasticity, responding rapidly to …
Environmental and genetic regulation of Streptococcus pneumoniae galactose catabolic pathways
BO Kareem, O Gazioglu, K Mueller Brown… - Nature …, 2024 - nature.com
Efficient utilization of nutrients is crucial for microbial survival and virulence. The same
nutrient may be utilized by multiple catabolic pathways, indicating that the physical and …
nutrient may be utilized by multiple catabolic pathways, indicating that the physical and …
The pneumococcal social network
Gram-positive bacteria employ an array of secreted peptides to control population-level
behaviors in response to environmental cues. We review mechanistic and functional …
behaviors in response to environmental cues. We review mechanistic and functional …
The Rgg1518 transcriptional regulator is a necessary facet of sugar metabolism and virulence in Streptococcus pneumoniae
Rggs are a group of transcriptional regulators with diverse roles in metabolism and
virulence. Here, we present work on the Rgg1518/SHP1518 quorum sensing system of …
virulence. Here, we present work on the Rgg1518/SHP1518 quorum sensing system of …
Identification and characterization of negative regulators of rgg1518 quorum sensing in streptococcus pneumoniae
D Hu, I Laczkovich, MJ Federle… - Journal of …, 2023 - Am Soc Microbiol
Streptococcus pneumoniae is an agent of otitis media, septicemia, and meningitis and
remains the leading cause of community-acquired pneumonia regardless of vaccine use. Of …
remains the leading cause of community-acquired pneumonia regardless of vaccine use. Of …
Modulation of quorum sensing-associated virulence in bacteria: carbohydrate as a key factor
S Suresh, PP Alva, R Premanath - Archives of Microbiology, 2021 - Springer
Quorum sensing (QS) is a method of inter-cellular communication that permits bacteria to
dispense information about cell density and to synchronize the gene expression …
dispense information about cell density and to synchronize the gene expression …
Glutamate Dehydrogenase (GdhA) of Streptococcus pneumoniae is required for high temperature adaptation
During its progression from the nasopharynx to other sterile and nonsterile niches of its
human host, Streptococcus pneumoniae must cope with changes in temperature. We …
human host, Streptococcus pneumoniae must cope with changes in temperature. We …
Peptide maturation molecules act as molecular gatekeepers to coordinate cell-cell communication in Streptococcus pneumoniae
KM Brown, R Eutsey, O Gazioglu, D Wang, A Vallon… - Cell Reports, 2024 - cell.com
The human pathogen Streptococcus pneumoniae (Spn) encodes several cell-cell
communication systems, notably multiple members of the Rgg/SHP and the Tpr/Phr families …
communication systems, notably multiple members of the Rgg/SHP and the Tpr/Phr families …