The intrinsic electrical properties and the synaptic input-output relationships of neurons are
governed by the action of voltage-dependent ion channels. The localization of specific …

Monitoring the behavior of single molecules in living cells is a powerful approach to
investigate the details of cellular processes. Owing to their optical, chemical and …

Diffusion in the plasma membrane of living cells is often found to display anomalous
dynamics. However, the mechanism underlying this diffusion pattern remains highly …

Kv2. 1 exhibits two distinct forms of localization patterns on the neuronal plasma membrane:
One population is freely diffusive and regulates electrical activity via voltage-dependent K+ …

Stomata of plant leaves open to enable CO2 entry for photosynthesis and close to reduce
water loss via transpiration. Compared with photosynthesis, stomata respond slowly to …

Membrane contacts between endoplasmic reticulum (ER) and plasma membrane (PM), or
ER-PM junctions, are ubiquitous in eukaryotic cells and are platforms for lipid and calcium …

The voltage‐sensitive sodium channel Nav1. 5 (encoded by SCN5A) is expressed in
electromechanical organs and is mechanosensitive. This study aimed to determine the …

Junctions between cortical endoplasmic reticulum (cER) and the plasma membrane are a
subtle but ubiquitous feature in mammalian cells; however, very little is known about the …

Gap junctional channels are a class of membrane channels composed of transmembrane
channel-forming integral membrane proteins termed connexins, innexins or pannexins that …

The Kv2. 1 K+ channel is highly expressed throughout the brain, where it regulates
excitability during periods of high-frequency stimulation. Kv2. 1 is unique among Kv …