Chronic traumatic encephalopathy (CTE): criteria for neuropathological diagnosis and relationship to repetitive head impacts

AC McKee, TD Stein, BR Huber, JF Crary… - Acta …, 2023 - Springer
Over the last 17 years, there has been a remarkable increase in scientific research
concerning chronic traumatic encephalopathy (CTE). Since the publication of NINDS–NIBIB …

Traumatic brain injury and risk of neurodegenerative disorder

BL Brett, RC Gardner, J Godbout, K Dams-O'Connor… - Biological …, 2022 - Elsevier
Traumatic brain injury (TBI), particularly of greater severity (ie, moderate to severe), has
been identified as a risk factor for all-cause dementia and Parkinson's disease, with risk for …

Leveraging football accelerometer data to quantify associations between repetitive head impacts and chronic traumatic encephalopathy in males

DH Daneshvar, ES Nair, ZH Baucom, A Rasch… - Nature …, 2023 - nature.com
Chronic traumatic encephalopathy (CTE) is a neurodegenerative tauopathy associated with
repetitive head impacts (RHI), but the components of RHI exposure underlying this …

Understanding neurodegeneration after traumatic brain injury: from mechanisms to clinical trials in dementia

NSN Graham, DJ Sharp - Journal of Neurology, Neurosurgery & …, 2019 - jnnp.bmj.com
Traumatic brain injury (TBI) leads to increased rates of dementia, including Alzheimer's
disease. The mechanisms by which trauma can trigger neurodegeneration are increasingly …

Vascular contributions to cognitive impairment and dementia (VCID): A report from the 2018 National Heart, Lung, and Blood Institute and National Institute of …

BV Zlokovic, RF Gottesman, KE Bernstein… - Alzheimer's & …, 2020 - Wiley Online Library
Vascular contributions to cognitive impairment and dementia (VCID) are characterized by
the aging neurovascular unit being confronted with and failing to cope with biological insults …

A review of the molecular mechanisms of traumatic brain injury

AA Ladak, SA Enam, MT Ibrahim - World neurosurgery, 2019 - Elsevier
Traumatic brain injury (TBI) refers to any insult to the brain resulting in primary (direct) and
secondary (indirect) damage to the brain parenchyma. Secondary damage is often linked to …

Blood-brain barrier dysfunction in aging induces hyperactivation of TGFβ signaling and chronic yet reversible neural dysfunction

VV Senatorov Jr, AR Friedman, DZ Milikovsky… - Science Translational …, 2019 - science.org
Aging involves a decline in neural function that contributes to cognitive impairment and
disease. However, the mechanisms underlying the transition from a young-and-healthy to …

Assessing the severity of traumatic brain injury—time for a change?

O Tenovuo, R Diaz-Arrastia, LE Goldstein… - Journal of clinical …, 2021 - mdpi.com
Traumatic brain injury (TBI) has been described to be man's most complex disease, in man's
most complex organ. Despite this vast complexity, variability, and individuality, we still …

Traumatic brain injury (TBI) in collision sports: Possible mechanisms of transformation into chronic traumatic encephalopathy (CTE)

TB VanItallie - Metabolism, 2019 - Elsevier
Traumatic brain injury (TBI) is a leading cause of death and disability, contributing to~ 30%
of all injury-related deaths in the US. TBI occurs when a force transmitted to the head causes …

Diffuse axonal injury predicts neurodegeneration after moderate–severe traumatic brain injury

NSN Graham, A Jolly, K Zimmerman, NJ Bourke… - Brain, 2020 - academic.oup.com
Traumatic brain injury is associated with elevated rates of neurodegenerative diseases such
as Alzheimer's disease and chronic traumatic encephalopathy. In experimental models …