Systemic aging influences various physiological processes and contributes to structural and
functional decline in cardiac tissue. These alterations include an increased incidence of left …

Cardiorenal syndrome (CRS) involves bidirectional crosstalk between the failing heart and
the kidneys. Depending on the primum movens (primary cardiac or renal injury), systems …

Abstract Dapagliflozin (DAPA), a sodium-glucose cotransporter 2 (SGLT2) inhibitor, is well-
recognized for its therapeutic benefits in type 2 diabetes (T2D) and cardiovascular diseases …

Drug repurposing is a promising strategy for managing cardiovascular disease (CVD) in
geriatric populations, offering efficient and cost-effective solutions. CVDs are prevalent …

Metformin was developed from an offshoot of Guanidine. It is known to be the first-line
medication for type 2 diabetes mellitus, polycystic ovarian syndrome, and weight reduction …

Chronic kidney disease (CKD) is a progressive and incurable condition that imposes a
significant burden on an aging society. Although the exact prevalence of this disease is …

Hypoglycemic medications are widely used in managing diabetes mellitus, with emerging
evidence suggesting their role in cardiac reverse remodeling. This systematic review aims to …

Sodium glucose cotransporter type 2 inhibitors are a new class of drugs that act on the
cardiovascular system, kidneys and metabolism in a multiple ways. Indeed, even though …

Cardiovascular diseases (CVDs), including ischemic heart disease and stroke, are the
leading cause of mortality worldwide, causing nearly 20 million deaths annually. Traditional …

Cardiovascular diseases (CVDs), including ischemic heart disease and stroke, are the
leading cause of mortality worldwide, causing nearly 20 million deaths annually. Traditional …