The impact of infections and inflammation during pregnancy on the developing fetal brain
remains incompletely defined, with important clinical and research gaps. Although the …

All mammalian species depend on the placenta, a transient organ, for exchange of gases,
nutrients, and waste between the mother and conceptus. Besides serving as a conduit for …

Psychomotor abnormalities have been abundantly observed in psychiatric disorders like
major depressive disorder (MDD), bipolar disorder (BD), and schizophrenia (SCH). Although …

Starting from the Developmental Origins of Health and Disease (DOHaD) hypotheses
proposed by David Barker, namely fetal programming, in the past years, there is a growing …

The placenta is a transient organ but essential for the survival of all mammalian species by
allowing for the exchanges of gasses, nutrients, and waste between maternal and fetal …

Serotonin (5-HT) is a critical player in brain development and neuropsychiatric disorders.
Fetal 5-HT levels can be influenced by several gestational factors, such as maternal …

l-Tryptophan is an essential amino acid and a precursor of several physiologically active
metabolites. In the placenta, the serotonin and kynurenine metabolic pathways of tryptophan …

Impairments in social interaction and communication, in combination with restricted,
repetitive behaviors and interests, define the neurodevelopmental diagnosis of autism …

In rodent models of Autism Spectrum Disorders (ASD), the study of ultrasonic vocalizations
has provided the unique opportunity to evaluate social communication and interaction in …

Abstract Purpose of Review To review the literature and detail the potential immune
mechanisms by which hyperserotonemia may drive pro-inflammation in preeclampsia and to …