Phenoxazine-based red-emitting fluorescence probe for specific detection and imaging of endogenous neutrophil elastase in vitro and in vivo

X Li, Y Qiu, X Luo, G Liu, Q Sun - Dyes and Pigments, 2023 - Elsevier
Neutrophil elastase is a crucial serine protease, which can be acted as a biomarker of
inflammatory-related diseases. Therefore, visual monitoring of NE level is of great …

Optimization of fluorescent substrates for ADAM17 and their utility in the detection of diabetes

H Sikora, N Gruba, M Wysocka, A Piwkowska… - Analytical …, 2023 - Elsevier
ADAM17 (ad isintegrin and m etalloproteinase 17) is a sheddase that releases various types
of membrane-associated proteins, including adhesive molecules, cytokines and their …

Caspase-like activity is associated with bacterial infection of the urine in urinary tract diseases

N Gruba, H Sikora, J Ciesielska, W Rejmak… - Analytical …, 2024 - Elsevier
Urinary tract infections (UTIs) are a serious public health problem. They can be caused by a
number of pathogens, but the most common are Escherichia coli, Klebsiella pneumoniae …

Chemical tools to monitor bladder cancer progression

N Gruba, L Stachurski, A Lesner - Biomarkers, 2022 - Taylor & Francis
Abstract Background Bladder cancer (BCa) is the most common cancer of the urinary
system. Due to its high incidence and recurrence, as well as limited progress in the effective …

Wykorzystanie enzymów w diagnostyce medycznej

N Gruba - Wiadomości Chemiczne, 2023 - yadda.icm.edu.pl
Each tissue has its own specific enzyme profile. Therefore, the detection of changes in the
level of certain enzymes in disease states allows conclusions about the location and type of …

[PDF][PDF] Monitorowanie aktywności proteolitycznej jako element diagnostyki chorób cywilizacyjnych

N Gruba, A Romanowska, W Rejmak… - Wiadomości …, 2022 - bibliotekanauki.pl
Proteolytic enzymes are essential for the proper functioning of every living cell. Due to their
great importance in controlling metabolic changes in living organisms, they could be used in …