The emergence of drug resistance has created unmet medical need for the development of
new classes of antibiotics. Innovation of new antibacterial agents with new mode of action …

Thiophene has emerged as a potent scaffold that has pulled the keen interest of the
researchers because of its considerable diversity in biological activities. The versatility of the …

The antibiotic resistance problems constitute a considerable threat to human health
worldwide; thus, the discovery of new antimicrobial candidates to conquer this issue is an …

A series of novel benzimidazole derivatives were synthesized and characterized by 1H
NMR, 13C NMR, MS, IR and HRMS spectra. All the new compounds were screened for their …

A TiCl4 promoted formal [3+ 3] cycloaddition of cyclopropane 1, 1-diesters with azides has
been developed for the synthesis of highly functionalized triazinines. Both stoichiometric and …

In this study, we designed and synthesized a series of thiophen-2-iminothiazolidine
derivatives from thiophen-2-thioureic with good anti-Trypanosoma cruzi activity. Several of …

This paper described our efforts to develop dianilinopyrimidines as novel EGFR inhibitors.
All the target compounds were tested for inhibitory effects against wild type EGFR (EGFRwt) …

Pyridine‐2 (1H)‐thiones were prepared and reacted with several active halogenated
reagents to afford novel thieno [2, 3‐b] pyridines in excellent yields. Thieno [2, 3‐b] pyridine …

1, 2, 3-Triazine is an interesting class of heterocyclic compounds. Various synthetic analogs
of 1, 2, 3-triazine have been prepared and evaluated for many pharmacological activities in …

Benzene is a six-membered hydrocarbon ring system and if three carbon-hydrogen units of
benzene ring are replaced by nitrogen atoms then triazine is formed. Triazines are present …