[HTML][HTML] Benzodiazepines: uses, dangers, and clinical considerations

AN Edinoff, CA Nix, J Hollier, CE Sagrera… - Neurology …, 2021 - mdpi.com
Benzodiazepines (BZDs) are among one of the most widely prescribed drug classes in the
United States. BZDs are a class of psychoactive drugs known for their depressant effect on …

Benzodiazepines remain important therapeutic options in psychiatric practice

SL Dubovsky, D Marshall - Psychotherapy and Psychosomatics, 2022 - karger.com
Benzodiazepines and medications acting on benzodiazepine receptors that do not have a
benzodiazepine structure (z-drugs) have been viewed by some experts and regulatory …

Benzodiazepines in Alzheimer's disease: beneficial or detrimental effects

HM Al-Kuraishy, AI Al-Gareeb, HM Saad… - …, 2023 - Springer
Dementia is considered a clinical syndrome characterized by cognitive dysfunction and
memory loss. Alzheimer's disease (AD) is the most common type of dementia. AD is linked …

Insights on benzodiazepines' potential in Alzheimer's disease

HM Al-Kuraishy, AI Al-Gareeb, AA Alsayegh… - Life Sciences, 2023 - Elsevier
Alzheimer's disease (AD) is the most frequent type of dementia characterized by the
deposition of amyloid beta (Aβ) plaque and tau-neurofibrillary tangles (TNTs) in the brain …

[HTML][HTML] Developing an explainable machine learning-based personalised dementia risk prediction model: A transfer learning approach with ensemble learning …

SO Danso, Z Zeng, G Muniz-Terrera… - Frontiers in big Data, 2021 - frontiersin.org
Alzheimer's disease (AD) has its onset many decades before dementia develops, and work
is ongoing to characterise individuals at risk of decline on the basis of early detection …

Benzodiazepines and antidepressants: Effects on cognitive and functional decline in Alzheimer's disease and Lewy body dementia

MG Borda, A Jaramillo‐Jimenez… - … Journal of Geriatric …, 2021 - Wiley Online Library
Objectives We aim to study the effects of the prescription of benzodiazepines and
antidepressants on cognitive and functional decline in older adults living with Alzheimer's …

[HTML][HTML] Gait speed, cognition and falls in people living with mild-to-moderate Alzheimer disease: data from NILVAD

AH Dyer, B Lawlor, SP Kennelly - BMC geriatrics, 2020 - Springer
Background Previous evidence suggests that slower gait speed is longitudinally associated
with cognitive impairment, dementia and falls in older adults. Despite this, the longitudinal …

[HTML][HTML] Mapping new pharmacological interventions for cognitive function in Alzheimer's disease: a systematic review of randomized clinical trials

I Xu Lou, J Chen, K Ali, AL Shaikh… - Frontiers in Pharmacology, 2023 - frontiersin.org
Background and Objective: Alzheimer's disease (AD) is a progressive neurodegenerative
disorder, that is, characterized by cognitive decline. To date, there are no effective …

[HTML][HTML] Association between Z drugs use and risk of cognitive impairment in middle-aged and older patients with chronic insomnia

F Guo, L Yi, W Zhang, ZJ Bian… - Frontiers in Human …, 2021 - frontiersin.org
Background: Benzodiazepines (BZDs) and Non-BZDs (NBZDs) have been widely used for
patients with chronic insomnia. Long-term uses of BZDs may cause cognitive impairment …

Relationships of Hypnotics with Incident Dementia and Alzheimer's Disease: A Longitudinal Study and Meta-Analysis

JH Hou, SL Sun, CC Tan, YM Huang, L Tan… - The Journal of …, 2024 - Springer
Background Evidence describing the association between hypnotics use and dementia risk
is conflicting. It is unknown if the controversy is related to the type or dose of hypnotics or if …