Polyunsaturated fatty acids and fatty acid-derived lipid mediators: Recent advances in the understanding of their biosynthesis, structures, and functions
Polyunsaturated fatty acids (PUFAs) are structural components of membrane phospholipids,
and influence cellular function via effects on membrane properties, and also by acting as a …
and influence cellular function via effects on membrane properties, and also by acting as a …
COVID-19: the inflammation link and the role of nutrition in potential mitigation
The novel coronavirus disease (COVID-19) pandemic caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has engulfed the world, affecting more than 180 …
syndrome coronavirus 2 (SARS-CoV-2) has engulfed the world, affecting more than 180 …
Vitamin D and marine omega 3 fatty acid supplementation and incident autoimmune disease: VITAL randomized controlled trial
J Hahn, NR Cook, EK Alexander, S Friedman, J Walter… - Bmj, 2022 - bmj.com
Objective To investigate whether vitamin D and marine derived long chain omega 3 fatty
acids reduce autoimmune disease risk. Design Vitamin D and omega 3 trial (VITAL), a …
acids reduce autoimmune disease risk. Design Vitamin D and omega 3 trial (VITAL), a …
Specialized pro-resolving mediator network: an update on production and actions
Today, persistent and uncontrolled inflammation is appreciated to play a pivotal role in many
diseases, such as cardiovascular diseases, neurodegenerative diseases, metabolic …
diseases, such as cardiovascular diseases, neurodegenerative diseases, metabolic …
Resolution of inflammation: An organizing principle in biology and medicine
D Panigrahy, MM Gilligan, CN Serhan… - Pharmacology & …, 2021 - Elsevier
The resolution of inflammation has emerged as a critical endogenous process that protects
host tissues from prolonged or excessive inflammation that can become chronic. Failure of …
host tissues from prolonged or excessive inflammation that can become chronic. Failure of …
Eicosapentaenoic and docosahexaenoic acid derived specialised pro-resolving mediators: Concentrations in humans and the effects of age, sex, disease and …
PC Calder - Biochimie, 2020 - Elsevier
Although inflammation has a physiological role, unrestrained inflammation can be
detrimental, causing tissue damage and disease. Under normal circumstances inflammation …
detrimental, causing tissue damage and disease. Under normal circumstances inflammation …
Platelet activation and prothrombotic mediators at the nexus of inflammation and atherosclerosis: Potential role of antiplatelet agents
Platelets are central to inflammation-related manifestations of cardiovascular diseases
(CVD) such as atherosclerosis. Platelet-activating factor (PAF), thrombin, thromboxane A 2 …
(CVD) such as atherosclerosis. Platelet-activating factor (PAF), thrombin, thromboxane A 2 …
n-3 PUFA and inflammation: from membrane to nucleus and from bench to bedside
PC Calder - Proceedings of the Nutrition Society, 2020 - cambridge.org
Inflammation is a normal part of the immune response and should be self-limiting. Excessive
or unresolved inflammation is linked to tissue damage, pathology and ill health …
or unresolved inflammation is linked to tissue damage, pathology and ill health …
Specialized pro-resolving mediators in vascular inflammation and atherosclerotic cardiovascular disease
Timely resolution of the acute inflammatory response (or inflammation resolution) is an
active, highly coordinated process that is essential to optimal health. Inflammation resolution …
active, highly coordinated process that is essential to optimal health. Inflammation resolution …
Resolvins and cysteinyl-containing pro-resolving mediators activate resolution of infectious inflammation and tissue regeneration
This review is a synopsis of the main points from the opening presentation by the authors in
the Resolution of Inflammation session at the 8th European Workshop on Lipid Mediators …
the Resolution of Inflammation session at the 8th European Workshop on Lipid Mediators …