In addition to ATP synthesis, mitochondria are highly dynamic organelles that modulate
apoptosis, ferroptosis, and inflammasome activation. Through executing these varied …

Neurodegenerative diseases are a heterogeneous group of disorders that are incurable and
characterized by the progressive degeneration of the function and structure of the central …

Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by the
deposition of β-amyloid (Aβ) peptides and dysfunction of mitochondrion, which result in …

Neurodegenerative diseases represent some of the most devastating neurological
disorders, characterized by progressive loss of the structure and function of neurons. Current …

Neurodegenerative disorders are debilitating diseases of the brain, characterized by
behavioral, motor and cognitive impairments. Ample evidence underpins mitochondrial …

There is increasing evidence for the involvement of mitochondrial dysfunction and oxidative
stress in the pathogenesis of many of the major neurodegenerative and neuroinflammatory …

The constant high energy demand of neurons makes them rely heavily on their
mitochondria. Dysfunction of mitochondrial energy metabolism leads to reduced ATP …

Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors and they serve to
be a promising therapeutic target for several neurodegenerative disorders, which includes …

Background and Purpose Phytocannabinoids are produced in Cannabis sativa L. in acidic
form and are decarboxylated upon heating, processing and storage. While the biological …

Thiazolidinedione (TZD) drugs used in the treatment of type 2 diabetes mellitus (T2DM)
have proven effective in improving insulin sensitivity, hyperglycemia, and lipid metabolism …