Stimuli-responsive polymeric nanoplatforms for cancer therapy

D Chang, Y Ma, X Xu, J Xie, S Ju - Frontiers in bioengineering and …, 2021 - frontiersin.org
Polymeric nanoparticles have been widely used as carriers of drugs and bioimaging agents
due to their excellent biocompatibility, biodegradability, and structural versatility. The …

Recent advances in functional polymer materials for energy, water, and biomedical applications: a review

Y El-Ghoul, FM Alminderej, FM Alsubaie, R Alrasheed… - Polymers, 2021 - mdpi.com
Academic research regarding polymeric materials has been of great interest. Likewise,
polymer industries are considered as the most familiar petrochemical industries. Despite the …

Pharmacogenetics of drug metabolism: the role of gene polymorphism in the regulation of doxorubicin safety and efficacy

AA Bagdasaryan, VN Chubarev, EA Smolyarchuk… - Cancers, 2022 - mdpi.com
Simple Summary The effectiveness and safety of the anti-cancer agent doxorubicin
(anthracycline group medicine) depend on the metabolism and retention of the drug in the …

[HTML][HTML] Doxorubicin-conjugated siRNA lipid nanoparticles for combination cancer therapy

K Butowska, X Han, N Gong, R El-Mayta… - … Pharmaceutica Sinica B, 2023 - Elsevier
Evasion of apoptosis is a hallmark of cancer, attributed in part to overexpression of the anti-
apoptotic protein B-cell lymphoma 2 (Bcl-2). In a variety of cancer types, including …

Overcoming the barriers of nuclear-targeted drug delivery using nanomedicine-based strategies for enhanced anticancer therapy

SM Roy, V Garg, SP Sivaraman, S Barman… - Journal of Drug Delivery …, 2023 - Elsevier
Targeted drug delivery is critical for improving the therapeutic benefits of anticancer drugs.
The active delivery strategy increases the bioavailability of drugs not only to the diseased …

One-pot synthesis of amphiphilic biopolymers from oxidized alginate and self-assembly as a carrier for sustained release of hydrophobic drugs

Z Liu, X Chen, Z Huang, H Wang, S Cao, C Liu, H Yan… - Polymers, 2022 - mdpi.com
In this paper, we developed an organic solvent-free, eco-friendly, simple and efficient one-
pot approach for the preparation of amphiphilic conjugates (Ugi-OSAOcT) by grafting …

Polymerization‐induced self‐assembly for drug delivery: A critical appraisal

EG Hochreiner… - Journal of Polymer …, 2023 - Wiley Online Library
Polymerization‐induced self‐assembly (PISA) with (in situ) encapsulation of (therapeutic)
cargo has proven to be an efficient preparation method for loaded polymeric micelles and …

Treating Alzheimer's disease using nanoparticle-mediated drug delivery strategies/systems

AK Roghani, RI Garcia, A Roghani, A Reddy… - Ageing Research …, 2024 - Elsevier
The administration of promising medications for the treatment of neurodegenerative
disorders (NDDs), such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's …

CD44-targeted nanoparticles with GSH-responsive activity as powerful therapeutic agents against breast cancer

M Brindisi, M Curcio, L Frattaruolo, G Cirillo… - International Journal of …, 2022 - Elsevier
DOX-loaded nanoparticles able to actively target CD44-receptors and respond to redox
stimuli were proposed as non-conventional chemotherapeutic strategy in breast cancer. A …

Synthesis and characterization of novel hybrid nanomaterials based on β-cyclodextrine grafted halloysite nanotubes for delivery of doxorubicin to MCF-7 cell line

V Shafiei-Irannejad, V Rahimkhoei… - Journal of Molecular …, 2022 - Elsevier
In the present study, the surface of halloysite nanotubes (Hal) grafted with a reactive β-
cyclodextrin based monomer carrying vinyl carboxylic acid functional groups (MAH-β-CD) …