Anthropometric and adiposity indicators and risk of type 2 diabetes: systematic review and dose-response meta-analysis of cohort studies

A Jayedi, S Soltani, SZ Motlagh, A Emadi, H Shahinfar… - Bmj, 2022 - bmj.com
Objective To present a comprehensive review of the association between measures of body
weight, waist, and fat, and different ratios of these measures, and the risk of type 2 diabetes …

Mechanism of ferroptosis and its role in type 2 diabetes mellitus

W Sha, F Hu, Y Xi, Y Chu, S Bu - Journal of diabetes research, 2021 - Wiley Online Library
Ferroptosis is a novel form of nonapoptotic regulated cell death (RCD). It features iron‐
dependent lipid peroxide accumulation accompanied by inadequate redox enzymes …

Iron metabolism and ferroptosis in type 2 diabetes mellitus and complications: mechanisms and therapeutic opportunities

R Miao, X Fang, Y Zhang, J Wei, Y Zhang… - Cell Death & Disease, 2023 - nature.com
The maintenance of iron homeostasis is essential for proper endocrine function. A growing
body of evidence suggests that iron imbalance is a key factor in the development of several …

Serum ferritin is an important inflammatory disease marker, as it is mainly a leakage product from damaged cells

DB Kell, E Pretorius - Metallomics, 2014 - academic.oup.com
Abstract" Serum ferritin" presents a paradox, as the iron storage protein ferritin is not
synthesised in serum yet is to be found there. Serum ferritin is also a well known …

Early prediction of developing type 2 diabetes by plasma acylcarnitines: a population-based study

L Sun, L Liang, X Gao, H Zhang, P Yao, Y Hu… - Diabetes …, 2016 - Am Diabetes Assoc
OBJECTIVE Acylcarnitines were suggested as early biomarkers even prior to insulin
resistance in animal studies, but their roles in predicting type 2 diabetes were unknown …

Causes of type 2 diabetes in China

RCW Ma, X Lin, W Jia - The Lancet Diabetes & Endocrinology, 2014 - thelancet.com
The prevalence of diabetes in China has increased substantially over recent decades, with
more than 100 million people estimated to be affected by the disease presently. During this …

Curcumin and (−)-epigallocatechin-3-gallate protect murine MIN6 pancreatic beta-cells against iron toxicity and erastin-induced ferroptosis

T Kose, M Vera-Aviles, PA Sharp, GO Latunde-Dada - Pharmaceuticals, 2019 - mdpi.com
Ferroptosis is a form of programmed cell death that is characterized by lipid peroxidation
and is inducible by iron and the accumulation of reactive oxygen species (ROS). It is …

Epidemiological associations between iron and cardiovascular disease and diabetes

D Basuli, RG Stevens, FM Torti, SV Torti - Frontiers in pharmacology, 2014 - frontiersin.org
Disruptions in iron homeostasis are linked to a broad spectrum of chronic conditions
including cardiovascular, malignant, metabolic, and neurodegenerative disease. Evidence …

Iron status in the elderly: A review of recent evidence

AA Wawer, A Jennings, SJ Fairweather-Tait - Mechanisms of ageing and …, 2018 - Elsevier
A comprehensive literature review of iron status in the elderly was undertaken in order to
update a previous review (Fairweather-Tait et al, 2014); 138 summarised papers describe …

The role of iron metabolism in chronic diseases related to obesity

F Qiu, L Wu, G Yang, C Zhang, X Liu, X Sun, X Chen… - Molecular …, 2022 - Springer
Obesity is one of the major public health problems threatening the world, as well as a
potential risk factor for chronic metabolic diseases. There is growing evidence that iron …