Multiple-system atrophy is a neurodegenerative disease characterized by progressive
autonomic failure, parkinsonism, and cerebellar and pyramidal tract symptoms. Glial …

Background Characterization of the mesenchymal stromal cell (MSC) safety profile is
important as this novel therapy continues to be evaluated in clinical trials for various …

In this study (trial registration: NCT02166021), we aimed to evaluate the optimal way of
administration, the safety and the clinical efficacy of mesenchymal stem cell (MSC) …

Backgrounds Alzheimer's disease is the most common cause of dementia, and currently,
there is no disease-modifying treatment. Favorable functional outcomes and reduction of …

Importance Preclinical studies have shown that neurotrophic growth factors (NTFs) extend
the survival of motor neurons in amyotrophic lateral sclerosis (ALS) and that the combined …

Mesenchymal stem cells (MSC s) have recently generated great interest in the fields of
regenerative medicine and immunotherapy due to their unique biologic properties. In this …

Stem cell-based therapies for neurodegenerative diseases aim at halting clinical
deterioration by regeneration and by providing local support for damaged tissue …

Mesenchymal stromal cells are multipotent cells that are being used to treat a variety of
medical conditions. Over the past decade, there has been considerable excitement about …

Mesenchymal stromal cells (MSCs) are multipotent cells found in different tissues: bone
marrow, peripheral blood, adipose tissues, skeletal muscle, perinatal tissues, and dental …

Accumulating evidence has shown that the paracrine factors derived from mesenchymal
stem cells (MSCs) are capable of regulating the immune system via interaction with various …