The objective of this comprehensive review is to summarize and discuss the available
evidence of how adipose tissue inflammation affects insulin sensitivity and glucose …

Obesity is an important aspect of the metabolic syndrome and is often associated with
chronic inflammation. In this context, inflammation of organs participating in energy …

Cancer cell growth requires fatty acids to replicate cellular membranes. The kinase Akt is
known to up-regulate fatty acid synthesis and desaturation, which is carried out by the …

ABSTRACT Stearoyl CoA desaturase 1 (SCD1) catalyzes the rate-limiting step in the
production of MUFA that are major components of tissue lipids. Alteration in SCD1 …

The consumption of an olive oil rich diet has been associated with the diminished incidence
of cardiovascular disease and cancer. Several studies have attributed these beneficial …

The widespread use of the inadequately defined term" leptin resistance" led the National
Institutes of Health to convene a workshop aimed at developing a quantitative definition of …

Stearoyl‐CoA desaturase 1 (SCD1) is an essential lipogenic enzyme that has been shown
to play an intrinsic role in the development of obesity and related conditions, such as insulin …

Different lipid fractions in humans have characteristic fatty acid profiles and these are
maintained partly through diet and to a lesser extent through endogenous synthesis. The …

Free fatty acids (FFAs) are metabolic intermediates that may be obtained through the diet or
synthesized endogenously. In addition to serving as an important source of energy, they …

The gut microbiota plays a key role in host metabolism. Toll-like receptor 5 (TLR5), a
flagellin receptor, is required for gut microbiota homeostasis. Accordingly, TLR5-deficient …