The transcription factor NF-κB is a central mediator of inflammation with multiple links to
thrombotic processes. In this review, we focus on the role of NF-κB signaling in cell types …

Platelets are chief cells in hemostasis. Apart from their hemostatic roles, platelets are major
inflammatory effector cells that can influence both innate and adaptive immune responses …

Antiplatelet treatment is of fundamental importance in combatting functions/dysfunction of
platelets in the pathogenesis of cardiovascular and inflammatory diseases. Dysfunction of …

When platelet numbers are low or when their function is disabled, the risk of bleeding is
high, which on the one hand indicates that in normal life vascular damage is a rather …

Beyond platelets function in hemostasis, there is emerging evidence to suggest that platelets
contribute crucially to inflammation and immune responses. Therefore, considering the …

Platelets contribute to processes beyond thrombus formation and may play a so far
underestimated role as an immune cell in various circumstances. This review outlines …

Activation of nuclear factor (NF)-κB, one of the most investigated transcription factors, has
been found to control multiple cellular processes in cancer including inflammation …

Platelets are chief effector cells in hemostasis. In addition, they are multifaceted
inflammatory cells with functions that span the continuum from innate immune responses to …

MicroRNAs (miRNAs) regulate cell physiology by altering protein expression, but the biology
of platelet miRNAs is largely unexplored. We tested whether platelet miRNA levels were …

Endothelial prostacyclin and nitric oxide potently inhibit platelet functions. Prostacyclin and
nitric oxide actions are mediated by platelet adenylyl and guanylyl cyclases, which …