[HTML][HTML] Colchicine—The Divine Medicine against COVID-19

V Mitev - Journal of Personalized Medicine, 2024 - mdpi.com
Colchicine has a number of effects that suggest it may be useful in the treatment of COVID-
19. Myeloid cells are a major source of dysregulated inflammation in COVID-19. The …

The NLRP3 inflammasome in allergic diseases: mechanisms and therapeutic implications

H Zhou, L Wang, W Lv, H Yu - Clinical and Experimental Medicine, 2024 - Springer
In recent years, there has been a global increase in the prevalence of allergic diseases,
including allergic rhinitis, chronic rhinosinusitis, allergic asthma, atopic dermatitis, allergic …

Recent Advances in NLRP3 Inflammasome in Corneal Diseases: Preclinical Insights and Therapeutic Implications

J Ge, X Li, Y Xia, Z Chen, C Xie, Y Zhao, K Chen… - The Ocular Surface, 2024 - Elsevier
NLRP3 inflammasome is a cytosolic multiprotein complex formed in response to exogenous
environmental stress and cellular damage. The three major components of the NLRP3 …

Expression of Intron-containing HIV-1 RNA Induces NLRP1 Inflammasome Activation in Myeloid Cells

S Jalloh, IK Hughes, H Akiyama, A Gojanovich… - bioRxiv, 2024 - biorxiv.org
Despite the success of antiretroviral therapy (ART) in suppressing plasma viremia in people
living with human immunodeficiency virus type-1 (HIV-1), persistent viral RNA expression in …

Exploring cell death mechanisms upon infection with respiratory syncytial virus

SL Trøen - 2024 - ntnuopen.ntnu.no
Respiratorisk syncytialt virus (RSV) utgjør en betydelig helseutfordring, og rammer spesielt
eldre, immunkompromitterte individer og små barn. Akutt lungeskade indusert av virus er …

Secukinumab'Cardioprotective Effect in Doxorubicin-induced cardiomyopathy: Targeting the NF-κB/NLRP3 Pathway in Rats

MD Hassen, NO Mousa, SM Radwan, RM Gabre - 2024 - researchsquare.com
Doxorubicin (DOX) is a medication employed in the treatment of cancer as a
chemotherapeutic agent. However, it induces cardiotoxicity via activating inflammatory …

Respiratory infection-and asthma-prone, low vaccine responder children demonstrate distinct mononuclear cell DNA methylation pathways

D Martino, N Schultz, R Kaur, SD van Haren… - Clinical …, 2024 - Springer
Background Infants with frequent viral and bacterial respiratory infections exhibit
compromised immunity to routine immunizations. They are also more likely to develop …