The current Coronavirus disease 2019 or COVID-19 pandemic has infected over two million
people and resulted in the death of over one hundred thousand people at the time of writing …

RNA silencing is a fundamental, evolutionarily conserved mechanism that regulates gene
expression in eukaryotes. It also functions as a primary immune defense in microbes, such …

Lipids play numerous indispensable cellular functions and are involved in multiple steps in
the replication cycle of viruses. Infections by human-pathogenic coronaviruses result in …

The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency.
Various omics results have been reported for COVID-19, but the molecular hallmarks of …

Abstract The coronavirus disease 2019 (COVID-19) caused by coronavirus SARS-CoV-2
infection has become a global pandemic due to the high viral transmissibility and …

Host cells possess the metabolic assets required for viral infection. Recent studies indicate
that control of the host's metabolic resources is a core host–pathogen interaction. Viruses …

Membrane association is a hallmark of the genome replication of positive-strand RNA
viruses [(+) RNA viruses]. All well-studied (+) RNA viruses remodel host membranes and …

Positive-strand (+) RNA viruses are important and emerging pathogens of humans, animals,
and plants. Upon infection, they induce the formation of specialized membranous replication …

Positive-strand RNA viruses are the largest group of RNA viruses on Earth and cellular
membranes are critical for all aspects of their life cycle, from entry and replication to exit. In …

Oxidative stress and chronic low-grade inflammation in the lungs are associated with aging
and may contribute to age-related immune dysfunction. To maintain lung homeostasis …