Epidemiology of inflammatory bowel disease in India: the great shift east

S Kedia, V Ahuja - Inflammatory intestinal diseases, 2017 - karger.com
Background: Inflammatory bowel disease (IBD), once considered to be a Western disease,
is increasingly being reported from India and other Asian countries. The present review …

Toll-like receptor signaling in depression

LK Figueroa-Hall, MP Paulus, J Savitz - Psychoneuroendocrinology, 2020 - Elsevier
Depression is one of the most prevalent, disabling, and costly mental illnesses currently
affecting over 300 million people worldwide. A subset of depressed patients display …

Pathobionts: mechanisms of survival, expansion, and interaction with host with a focus on Clostridioides difficile

H Chandra, KK Sharma, OH Tuovinen, X Sun… - Gut …, 2021 - Taylor & Francis
Pathobionts are opportunistic microbes that emerge as a result of perturbations in the
healthy microbiome due to complex interactions of various genetic, exposomal, microbial …

Associations between functional polymorphisms in the NFκB signaling pathway and response to anti-TNF treatment in Danish patients with inflammatory bowel …

S Bank, PS Andersen, J Burisch, N Pedersen… - The …, 2014 - nature.com
Antitumor necrosis factor-α (TNF-α) is used for treatment of severe cases of inflammatory
bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC). However …

Mechanisms of microbe–host interaction in Crohn's disease: dysbiosis vs. pathobiont selection

LF Buttó, M Schaubeck, D Haller - Frontiers in immunology, 2015 - frontiersin.org
Crohn's disease (CD) is a systemic chronic inflammatory condition mainly characterized by
discontinuous transmural pathology of the gastrointestinal tract and frequent extraintestinal …

Increased serum levels of lipopolysaccharide and antiflagellin antibodies in patients with diarrhea‐predominant irritable bowel syndrome

A Dlugosz, P Nowak, M D'amato… - …, 2015 - Wiley Online Library
Background Innate immune responses to conserved microbial products such as
lipopolysaccharide (LPS) and flagellin are likely important in microbial–host interactions and …

Toll-like receptors signaling: A complex network for NF-κB activation in B-cell lymphoid malignancies

S Ntoufa, MG Vilia, K Stamatopoulos, P Ghia… - Seminars in cancer …, 2016 - Elsevier
Malignancies of mature B cells are quite distinctive in originating from well-differentiated
cells. Hence, it is not paradoxical that, similar to their normal counterparts, most mature B …

Impact of curcumin on toll‐like receptors

M Boozari, AE Butler, A Sahebkar - Journal of cellular …, 2019 - Wiley Online Library
Toll‐like receptors (TLRs) have a pivotal role in the activation of innate immune response
and inflammation. TLRs can be divided into two subgroups including extracellular TLRs that …

Toll-like receptor 4: a promising crossroads in the diagnosis and treatment of several pathologies

MM Garcia, C Goicoechea, M Molina-Álvarez… - European Journal of …, 2020 - Elsevier
Abstract Toll-like receptor 4 (TLR4) is expressed in a wide variety of cells and is the central
component of the mammalian innate immune system. Since its discovery in 1997, TLR4 has …

[HTML][HTML] Inflammatory bowel disease in India-Past, present and future

G Ray - World journal of gastroenterology, 2016 - ncbi.nlm.nih.gov
There is rising incidence and prevalence of inflammatory bowel disease (IBD) in India
topping the Southeast Asian (SEA) countries. The common genes implicated in disease …