Internal ribosome entry site (IRES)-mediated translation and its potential for novel mRNA-based therapy development

R Marques, R Lacerda, L Romão - Biomedicines, 2022 - mdpi.com
Many conditions can benefit from RNA-based therapies, namely, those targeting internal
ribosome entry sites (IRESs) and their regulatory proteins, the IRES trans-acting factors …

Translational control of Human Epidermal Growth Factor Receptors, HER2 and HER4 in response to cellular stresses in breast cancer cells

A Edwards - 2023 - eprints.nottingham.ac.uk
The human epidermal growth factors (EGFR and HER2-4) are tyrosine kinase cell surface
receptors that play key roles in cell signalling, growth, and differentiation. However, HER2 …

[引用][C] Internal Ribosome Entry Site-Dependent Translation Dysregulation-Related Diseases

R Marques, R Lacerda, L Romão - Encyclopedia, 2022 - MDPI