Molecular responses to acute exercise and their relevance for adaptations in skeletal muscle to exercise training

B Egan, AP Sharples - Physiological Reviews, 2023 - journals.physiology.org
Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …

An examination and critique of current methods to determine exercise intensity

NA Jamnick, RW Pettitt, C Granata, DB Pyne… - Sports Medicine, 2020 - Springer
Prescribing the frequency, duration, or volume of training is simple as these factors can be
altered by manipulating the number of exercise sessions per week, the duration of each …

High-intensity exercise and mitochondrial biogenesis: current controversies and future research directions

DJ Bishop, J Botella, AJ Genders, MJC Lee… - …, 2019 - journals.physiology.org
It is well established that different types of exercise can provide a powerful stimulus for
mitochondrial biogenesis. However, there are conflicting findings in the literature, and a …

An overview of technical considerations when using quantitative real-time PCR analysis of gene expression in human exercise research

J Kuang, X Yan, AJ Genders, C Granata, DJ Bishop - PloS one, 2018 - journals.plos.org
Gene expression analysis by quantitative PCR in skeletal muscle is routine in exercise
studies. The reproducibility and reliability of the data fundamentally depend on how the …

Principles of exercise prescription, and how they influence exercise-induced changes of transcription factors and other regulators of mitochondrial biogenesis

C Granata, NA Jamnick, DJ Bishop - Sports Medicine, 2018 - Springer
Physical inactivity represents the fourth leading risk factor for mortality, and it has been
linked with a series of chronic disorders, the treatment of which absorbs~ 85% of healthcare …

Influence of training intensity on adaptations in acid/base transport proteins, muscle buffer capacity, and repeated-sprint ability in active men

C McGinley, DJ Bishop - Journal of Applied Physiology, 2016 - journals.physiology.org
McGinley C, Bishop DJ. Influence of training intensity on adaptations in acid/base transport
proteins, muscle buffer capacity, and repeated-sprint ability in active men. J Appl Physiol …

Twenty-four weeks of β-alanine supplementation on carnosine content, related genes, and exercise

B Saunders, V de Salles Painelli… - Medicine & Science in …, 2017 - irep.ntu.ac.uk
Introduction: Skeletal muscle carnosine content can be increased through [beta]-alanine
supplementation, but the maximum increase achievable with supplementation is unknown …

Discordant skeletal muscle gene and protein responses to exercise

DJ Bishop, NJ Hoffman, DF Taylor, NJ Saner… - Trends in Biochemical …, 2023 - cell.com
The ability of skeletal muscle to adapt to repeated contractile stimuli is one of the most
intriguing aspects of physiology. The molecular bases underpinning these adaptations …

Can the skeletal muscle carnosine response to beta-alanine supplementation be optimized?

P Perim, FM Marticorena, F Ribeiro, G Barreto… - Frontiers in …, 2019 - frontiersin.org
Carnosine is an abundant histidine-containing dipeptide in human skeletal muscle and
formed by beta-alanine and L-histidine. It performs various physiological roles during …

Utilization of lactic acid in human myotubes and interplay with glucose and fatty acid metabolism

J Lund, V Aas, RH Tingstad, A Van Hees, N Nikolić - Scientific reports, 2018 - nature.com
Once assumed only to be a waste product of anaerobe glycolytic activity, lactate is now
recognized as an energy source in skeletal muscles. While lactate metabolism has been …