Epigenetic modification refers to heritable changes in gene function that cannot be
explained by alterations in the DNA sequence. The current literature clearly demonstrates …

Exercise-induced adaptation is achieved by altering the epigenetic landscape of the entire
genome leading to the expression of genes involved in various processes including …

Cells have evolved multiple and sophisticated stress response mechanisms aiming to
prevent macromolecular (including proteins, lipids, and nucleic acids) damage and to …

Physical exercise represents one of the strongest physiological stimuli capable to induce
functional and structural modifications in all biological systems. Indeed, beside the …

All organisms and cells respond to various stress conditions such as environmental,
metabolic, or pathophysiological stress by generally upregulating, among others, the …

Regular physical activity is effective as prevention and treatment for different chronic
conditions related to the ageing processes. In fact, a sedentary lifestyle has been linked to a …

Supplementation with antioxidants received interest as suitable tool for preventing or
reducing exercise-related oxidative stress possibly leading to improvement of sport …

Background: Oxidative stress is involved in different pathophysiological states, such as
aging, inflammatory, cardiovascular and neurodegenerative diseases, by damaging several …

Regular physical activity can enhance immune function and effectively prevents the spread
of the cytokine response, thus reducing systemic low‐grade inflammation and improving …

Breast cancer (BC) is the most commonly diagnosed cancer among women worldwide and
the most common cause of cancer-related death. To date, it is still a challenge to estimate …