Structure‐based varieties of polymeric nanocarriers and influences of their physicochemical properties on drug delivery profiles
Carriers are equally important as drugs. They can substantially improve bioavailability of
cargos and safeguard healthy cells from toxic effects of certain therapeutics. Recently …
cargos and safeguard healthy cells from toxic effects of certain therapeutics. Recently …
Engineering precise sequence-defined polymers for advanced functions
Unlike natural macromolecules (eg, nucleic acids and proteins) possessing precisely
defined molar mass, chain sequence, chirality, and topology, synthetic polymers are typically …
defined molar mass, chain sequence, chirality, and topology, synthetic polymers are typically …
RNA-polymer hybrids via direct and site-selective acylation with the ATRP initiator and photoinduced polymerization
Combining synthetic polymers with RNA paves the way for creating RNA-based materials
with non-canonical functions. We have developed an acylation reagent that allows for direct …
with non-canonical functions. We have developed an acylation reagent that allows for direct …
Sequence-and stereo-defined macromolecules: properties and emerging functionalities
R Szweda - Progress in Polymer Science, 2023 - Elsevier
Natural macromolecules, such as proteins and nucleic acids, display various complex
functionalities in biological systems. These functionalities depend on the macromolecular …
functionalities in biological systems. These functionalities depend on the macromolecular …
The delivery of mRNA vaccines for therapeutics
Nitika, J Wei, AM Hui - Life, 2022 - mdpi.com
mRNA vaccines have been revolutionary in combating the COVID-19 pandemic in the past
two years. They have also become a versatile tool for the prevention of infectious diseases …
two years. They have also become a versatile tool for the prevention of infectious diseases …
Expanding the architectural horizon of nucleic-acid-polymer biohybrids by site-controlled incorporation of ATRP initiators in DNA and RNA
Modifying biomacromolecules with synthetic polymers has been a powerful approach to
developing multifunctional hybrid biomaterials for nanoscience and biomedical applications …
developing multifunctional hybrid biomaterials for nanoscience and biomedical applications …
Cicada Wing-Inspired Transparent Polystyrene Film Integrating Self-Cleaning, Antifogging, and Antibacterial Properties
Y Du, T Wu, W Zhou, C Li, C Ding, P Chen… - … Applied Materials & …, 2023 - ACS Publications
A transparent film integrating antifouling, antifogging, and antibacterial properties is crucial
for its application as a protective mask, goggles, or lens. Herein, applying dynamic injection …
for its application as a protective mask, goggles, or lens. Herein, applying dynamic injection …
Poly (β-amino ester) polymer library with monomer variation for mRNA delivery
HL Kim, G Saravanakumar, S Lee, S Jang, S Kang… - Biomaterials, 2025 - Elsevier
Non-viral vectors for mRNA delivery primarily include lipid nanoparticles (LNPs) and
polymers. While LNPs are known for their high mRNA delivery efficiency, they can induce …
polymers. While LNPs are known for their high mRNA delivery efficiency, they can induce …
Development of polypeptide-based materials toward messenger RNA delivery
Messenger RNA (mRNA)-based therapeutic agents have demonstrated significant potential
in recent times, particularly in the context of the COVID-19 pandemic outbreak. As a …
in recent times, particularly in the context of the COVID-19 pandemic outbreak. As a …