Reactive oxygen species are produced by all aerobic cells and are widely believed to play a
pivotal role in aging as well as a number of degenerative diseases. The consequences of …

This review is concerned with the structures and mechanisms of a superfamily of regulatory
GTP hydrolases (G proteins). G proteins include Ras and its close homologs, translation …

Sequences and available structures were compared for all the widely distributed
representatives of the P-loop GTPases and GTPase-related proteins with the aim of …

Most plant disease resistance (R) genes known today encode proteins with a central
nucleotide binding site (NBS) and a C-terminal Leu-rich repeat (LRR) domain. The NBS …

Nutrition science has evolved considerably in the past decade with new concepts and
discoveries. In response, advanced nutrition courses now encompass material on …

Heterotrimeric G proteins in vertebrates constitute a family molecular switches that transduce
the activation of a populous group of cell-surface receptors to a group of diverse effector …

Hypertrophy of myocytes in the heart ventricles is an important adaptation that in vivo occurs
in response to a requirement for increased contractile power. It involves changes at the level …

The ras proto-oncogene is frequently mutated in human tumors and functions to chronically
stimulate signal transduction cascades resulting in the synthesis or activation of specific …

Mammalian cells harbor three highly homologous and widely expressed members of the ras
family (H-ras, N-ras, and K-ras), but it remains unclear whether they play specific or …

Stomata form pores on leaf surfaces that regulate the uptake of CO2 for photosynthesis and
the loss of water vapour during transpiration. An increase in the cytosolic concentration of …