[HTML][HTML] Pregnancy Toxemia in ewes: a review of Molecular Metabolic mechanisms and Management Strategies

X Ji, N Liu, Y Wang, K Ding, S Huang, C Zhang - Metabolites, 2023 - mdpi.com
Pregnancy toxemia is a nutritional metabolic disease during late gestation in small
ruminants. The condition is characterized by disorders in carbohydrate and fat metabolism …

[HTML][HTML] Regulation of litter size in sheep (Ovis aries) by the GDF9 and BMP15 genes

Y Chen, X Shan, H Jiang, L Sun, Z Guo - Annals of Agricultural Sciences, 2023 - Elsevier
The mutation types GDF9 S395F and S427R increase the ovulation rate in heterozygotes,
while the homozygous form leads to infertility. This study presents a meta-analysis of GDF9 …

Novel indel variations of the sheep FecB gene and their effects on litter size

H Li, H Xu, Z Akhatayeva, H Liu, C Lin, X Han, X Lu… - Gene, 2021 - Elsevier
Various studies had shown that the FecB gene (also known as BMPRIB, BMPR1B or ALK-6)
was the major gene influencing sheep litter size, for which its SNPs' variations were …

[HTML][HTML] The expression and mutation of BMPR1B and its association with litter size in small-tail Han sheep (Ovis aries)

YL Wen, XF Guo, L Ma, XS Zhang… - Archives Animal …, 2021 - aab.copernicus.org
Previous studies have shown that BMPR1B promotes follicular development and ovarian
granulosa cell proliferation, thereby affecting ovulation in mammals. In this study, the …

[HTML][HTML] CREB1 Is involved in miR-134-5p-mediated endometrial stromal cell proliferation, apoptosis, and autophagy

X Li, X Yao, K Li, J Guo, K Deng, Z Liu, F Yang, Y Fan… - Cells, 2023 - mdpi.com
The successful establishment of endometrial receptivity is a key factor in ensuring the fertility
of ewes and their economic benefits. Hu sheep have attracted attention due to their high …

Selection signatures of litter size in Dazu black goats based on a whole genome sequencing mixed pools strategy

YJ Zhao, YF Huang - Molecular Biology Reports, 2019 - Springer
Litter size is considered to be the most important index for estimating domestic animal
productivity. Due to its complexity, the molecular mechanism of litter size has not been …

[HTML][HTML] Distribution of Runs of Homozygosity and Their Relationship with Candidate Genes for Productivity in Kazakh Meat–Wool Sheep Breed

M Amandykova, Z Akhatayeva, A Kozhakhmet… - Genes, 2023 - mdpi.com
Increasing the fertility of sheep remains one of the crucial issues of modern sheep breeding.
The Kazakh meat–wool sheep is an excellent breed with high meat and wool productivity …

[HTML][HTML] Detection of Novel Variations Related to Litter Size in BMP15 Gene of Luzhong Mutton Sheep (Ovis aries)

R Di, F Wang, P Yu, X Wang, X He, JM Mwacharo… - Animals, 2021 - mdpi.com
Simple Summary BMP15 is a critical gene in sheep reproduction. Most of its variations have
been reported in European sheep. In this study, the entire open reading frame (ORF) region …

Three Complete Linkage SNPs of GDF9 Gene Affect the Litter Size Probably Mediated by OCT1 in Hu Sheep

Y Li, W Jin, Y Wang, J Zhang, C Meng, H Wang… - DNA and Cell …, 2020 - liebertpub.com
Growth differentiation factor (GDF) 9 gene is involved in regulating reproductive traits in
animals, but little is known about the promoter, single-nucleotide polymorphisms (SNPs) …

[HTML][HTML] Identification of fecXG and fecB mutations and its association with litter size in Kacang and Boerka goat

MM Maskur, SN Depamede - Adv Anim Vet Sci, 2023 - researcherslinks.com
The Kacang goat is one of Indonesia's prolific native goat breeds, while the Boerka goat is a
crossbreed between Kacang and Boer goats. It is widely known that the ovulation rate and …