Atrial fibrillation (AF) is a highly prevalent arrhythmia, with substantial associated morbidity
and mortality. There have been significant management advances over the past 2 decades …

Nonischemic dilated cardiomyopathy (DCM) often has a genetic pathogenesis. Because of
the large number of genes and alleles attributed to DCM, comprehensive genetic testing …

Increased cardiac contractility during the fight-or-flight response is caused by β-adrenergic
augmentation of CaV1. 2 voltage-gated calcium channels,,–. However, this augmentation …

Ca2+ is a fundamental second messenger in all cell types and is required for numerous
essential cellular functions, including cardiac and skeletal muscle contraction. The …

Each heartbeat is initiated by the action potential, an electrical signal that depolarizes the
plasma membrane and activates a cycle of calcium influx via voltage-gated calcium …

Atrial fibrillation (AF) is an extremely prevalent arrhythmia that presents a wide range of
therapeutic challenges. AF usually begins in a self-terminating paroxysmal form (pAF). With …

Cardiac arrhythmias are a significant cause of morbidity and mortality worldwide, accounting
for 10% to 15% of all deaths. Although most arrhythmias are due to acquired heart disease …

Dilated cardiomyopathy (DCM) frequently affects relatively young, economically, and
socially active adults, and is an important cause of heart failure and transplantation. DCM is …

Cardiac arrhythmias can follow disruption of the normal cellular electrophysiological
processes underlying excitable activity and their tissue propagation as coherent wavefronts …

Purpose To investigate the role and mechanism of quercetin in isoprenaline (ISO)-induced
atrial fibrillation (AF). Study design Rat cardiac fibroblasts (RCFs) models and RCFs were …