Developing safe and effective delivery strategies for localizing messenger RNA (mRNA)
payloads to the spleen is an important goal in the field of genetic medicine. Accomplishing …

Abstract IKK‐NF‐κB signaling is regarded as an important factor in hepatocarcinogenesis
and a potential target for liver cancer therapy. Therefore, in this study, we analyzed the …

Background Systematic approaches for identifying proteins involved in different types of
cancer are needed. Experimental techniques such as microarrays are being used to …

More than a decade ago, a number of methods were proposed for the inference of protein
interactions, using whole-genome information from gene clusters, gene fusions and …

BACKGROUND Castration‐resistant prostate cancer (CRPC) represents a challenge to treat
with no effective treatment options available. We recently identified serum response factor …

IGF-II plays a crucial role in fetal and cancer development by signaling through the IGF-I
receptor. We have shown that inhibition of IGF-II by resveratrol (RSV) induced apoptosis and …

In earlier studies, we have shown that cigarette smoke condensate (CSC), a surrogate for
cigarette smoke, is capable of transforming the spontaneously immortalized human breast …

Abstract Indole-3-carbinol (I3C), a dietary chemopreventive compound, induces cell death in
human breast cancer cells by modulating activities of Src and epidermal growth factor …

Cancer is a multifactorial disease in which cell types lost their capability to regulate growth,
proliferation, and cell death pathways, causing the uncontrolled proliferation of tumor cells …

Cells are dynamical systems characterized by a high degree of complexity due to an
intricate network of subcellular processes that sustain their correct performance. This …