Point prevalence study of antimicrobial use among hospitals across Botswana; findings and implications
BD Anand Paramadhas, C Tiroyakgosi… - Expert review of anti …, 2019 - Taylor & Francis
Objective: There is an urgent need to undertake Point Prevalence Surveys (PPS) across
Africa to document antimicrobial utilisation rates given high rates of infectious diseases and …
Africa to document antimicrobial utilisation rates given high rates of infectious diseases and …
The impact of digital technologies on point-of-care diagnostics in resource-limited settings
N Gous, DI Boeras, B Cheng, J Takle… - Expert review of …, 2018 - Taylor & Francis
Introduction: Simple, rapid tests that can be used at the point-of-care (POC) can improve
access to diagnostic services and overall patient management in resource-limited settings …
access to diagnostic services and overall patient management in resource-limited settings …
Ongoing initiatives to improve the use of antibiotics in Botswana: University of Botswana symposium meeting report
C Tiroyakgosi, M Matome, E Summers… - Expert review of anti …, 2018 - Taylor & Francis
Background and objective: There are ongoing initiatives in Botswana to enhance
appropriate antibiotic use. The objective of this meeting was to discuss ongoing initiatives in …
appropriate antibiotic use. The objective of this meeting was to discuss ongoing initiatives in …
Population structure and implications on the genetic architecture of HIV-1 phenotypes within Southern Africa
PK Thami, ER Chimusa - Frontiers in Genetics, 2019 - frontiersin.org
The interesting history of Southern Africa has put the region in the spotlight for population
medical genetics. Major events including the Bantu expansion and European colonialism …
medical genetics. Major events including the Bantu expansion and European colonialism …
Patients with presumed tuberculosis in sub-Saharan Africa that are not diagnosed with tuberculosis: a systematic review and meta-analysis
S Jayasooriya, F Dimambro-Denson, C Beecroft… - Thorax, 2023 - thorax.bmj.com
Background Many patients in sub-Saharan Africa whom a diagnosis of tuberculosis is
considered are subsequently not diagnosed with tuberculosis. The proportion of patients this …
considered are subsequently not diagnosed with tuberculosis. The proportion of patients this …
A root-cause analysis of maternal deaths in Botswana: towards developing a culture of patient safety and quality improvement
FD Madzimbamuto, SC Ray, KD Mogobe… - BMC pregnancy and …, 2014 - Springer
Abstract Background In 2007, 95% of women in Botswana delivered in health facilities with
73% attending at least 4 antenatal care visits. HIV-prevalence in pregnant women was …
73% attending at least 4 antenatal care visits. HIV-prevalence in pregnant women was …
A novel reporter phage to detect tuberculosis and rifampin resistance in a high-HIV-burden population
Improved diagnostics and drug susceptibility testing for Mycobacterium tuberculosis are
urgently needed. We developed a more powerful mycobacteriophage (Φ2GFP10) with a …
urgently needed. We developed a more powerful mycobacteriophage (Φ2GFP10) with a …
Research activities to improve the utilization of antibiotics in Africa
A Massele, C Tiroyakgosi, M Matome… - Expert review of …, 2017 - Taylor & Francis
There is a need to improve the rational use of antibiotics across continents including Africa.
This has resulted in initiatives in Botswana including treatment guidelines and the instigation …
This has resulted in initiatives in Botswana including treatment guidelines and the instigation …
Early detection of emergent extensively drug-resistant tuberculosis by flow cytometry-based phenotyping and whole-genome sequencing
MR O'Donnell, MH Larsen, TS Brown… - Antimicrobial agents …, 2019 - Am Soc Microbiol
ABSTRACT A critical gap in tuberculosis (TB) treatment is detection of emergent drug
resistance. We hypothesized that advanced phenotyping with whole-genome sequencing …
resistance. We hypothesized that advanced phenotyping with whole-genome sequencing …
Implementation and operational research: what happens after a negative test for tuberculosis? Evaluating adherence to TB diagnostic algorithms in South African …
KM McCarthy, AD Grant, V Chihota… - JAIDS Journal of …, 2016 - journals.lww.com
Methods: The XTEND (Xpert for TB—Evaluating a New Diagnostic) trial compared outcomes
among people tested for TB in primary care clinics using Xpert MTB/RIF vs. smear …
among people tested for TB in primary care clinics using Xpert MTB/RIF vs. smear …