Abstract Streptococcus pyogenes (Group A Streptococcus; GAS) is exquisitely adapted to
the human host, resulting in asymptomatic infection, pharyngitis, pyoderma, scarlet fever or …

Abstract Energy-coupling factor (ECF)-type transporters mediate the uptake of micronutrients
in many bacteria. They consist of a substrate-translocating subunit (S-component) and an …

Since the beginning of December 2022, unusually high numbers of cases and deaths
among children have been reported across the United Kingdom (UK) and other regional …

Antimicrobial resistance and tolerance are natural phenomena that arose due to
evolutionary adaptation of microorganisms against various xenobiotic agents. These …

The use of microalgae for antibiotic removal has received increasing attention due to its
many advantages. However, challenges such as limited removal rates and the complexity of …

Chemotherapy is widely used clinically, however, its efficacy is often compromised by the
development of drug resistance, which arises from prolonged administration of drugs or …

Emerging luminogens with aggregation-induced emission properties, namely AIEgens,
demonstrated excellent anti-bacteria activity potential. However, their application still limited …

Streptococcus pyogenes is a Gram-positive bacterium, also known as Group A
Streptococcus (GAS), that has become a significant threat to the healthcare system, infecting …

Streptococcus sanguinis is a prevalent member of human microbiome capable of acting as a
causative agent of oral and respiratory infections. S. sanguinis competitive success within …

In this thesis we mainly focus on membrane transporters that facilitate the transport of
vitamin B12 in bacteria. One of these transporters is the ABC transporters BacA from …