The role of macrophage subtypes and exosomes in immunomodulation

AT Gharavi, NA Hanjani, E Movahed… - Cellular & molecular …, 2022 - Springer
Macrophages are influential members of the innate immune system that can be reversibly
polarized by different microenvironment signals. Cell polarization leads to a wide range of …

Exosomal circular RNAs: a chief culprit in cancer chemotherapy resistance

X Guo, C Gao, DH Yang, S Li - Drug Resistance Updates, 2023 - Elsevier
Chemotherapy is one of the primary treatments for malignant tumors. However, the acquired
drug resistance hinders clinical efficacy and leads to treatment failure in most patients …

[HTML][HTML] Exosome nanovesicles: a potential carrier for therapeutic delivery

VP Chavda, A Pandya, L Kumar, N Raval, LK Vora… - Nano Today, 2023 - Elsevier
Exosomes are small nanosized biovesicles that form when multivesicular bodies and the
plasma membrane fuse and are released into the surrounding body fluids. They are best …

[HTML][HTML] Graph-based relevancy-redundancy gene selection method for cancer diagnosis

S Azadifar, M Rostami, K Berahmand, P Moradi… - Computers in Biology …, 2022 - Elsevier
Nowadays, microarray data processing is one of the most important applications in
molecular biology for cancer diagnosis. A major task in microarray data processing is gene …

Underlying features of prostate cancer—statistics, risk factors, and emerging methods for its diagnosis

CV Berenguer, F Pereira, JS Câmara, JAM Pereira - Current Oncology, 2023 - mdpi.com
Prostate cancer (PCa) is the most frequently occurring type of malignant tumor and a leading
cause of oncological death in men. PCa is very heterogeneous in terms of grade …

Mesenchymal stem cell-derived exosomes as a new therapeutic strategy in the brain tumors

E Ghasempour, S Hesami, E Movahed… - Stem Cell Research & …, 2022 - Springer
Brain tumors are one of the most mortal cancers, leading to many deaths among kids and
adults. Surgery, chemotherapy, and radiotherapy are available options for brain tumor …

[HTML][HTML] pH-sensitive ameliorated quercetin delivery using graphene oxide nanocarriers coated with potential anticancer gelatin-polyvinylpyrrolidone nanoemulsion …

AP Najafabadi, M Pourmadadi, F Yazdian… - Journal of Drug Delivery …, 2023 - Elsevier
The rapid rise of cancer worldwide demonstrates the importance of treatment strategies. In
addition to reduce the side effects of conventional treatments, targeted drug delivery systems …

Tumor-derived systems as novel biomedical tools—turning the enemy into an ally

N Desai, P Katare, V Makwana, S Salave… - Biomaterials …, 2023 - spj.science.org
Cancer is a complex illness that presents significant challenges in its understanding and
treatment. The classic definition," a group of diseases characterized by the uncontrolled …

Exosomes as rheumatoid arthritis diagnostic biomarkers and therapeutic agents

R Heydari, F Koohi, M Rasouli, K Rezaei… - Vaccines, 2023 - mdpi.com
Rheumatoid arthritis (RA) is a chronic inflammatory joint disorder that causes systemic
inflammation, autoimmunity, and joint abnormalities that result in permanent disability …

Nano based-oncolytic viruses for cancer therapy

M Ajam-Hosseini, F Akhoondi, M Doroudian - Critical Reviews in Oncology …, 2023 - Elsevier
Oncolytic viruses (OV) are an attractive prospect due to their dual attack mechanism of direct
cell lysis and potentiation of an antitumor immune response. Various oncolytic viral vectors …