Biochemical properties and roles of DprA protein in bacterial natural transformation, virulence, and pilin variation

DK Sharma, HS Misra, SC Bihani… - Journal of …, 2023 - Am Soc Microbiol
Natural transformation enables bacteria to acquire DNA from the environment and
contributes to genetic diversity, DNA repair, and nutritional requirements. DNA processing …

Gene regulation for the extreme resistance to ionizing radiation of Deinococcus radiodurans

W Wang, Y Ma, J He, H Qi, F Xiao, S He - Gene, 2019 - Elsevier
Deinococcus radiodurans is a model microorganism used for studies on DNA repair and
antioxidation due to its extraordinary tolerance to ionizing radiation and other DNA …

New Insights into Radio-Resistance Mechanism Revealed by (Phospho)Proteome Analysis of Deinococcus Radiodurans after Heavy Ion Irradiation

S Liu, F Wang, H Chen, Z Yang, Y Ning… - International Journal of …, 2023 - mdpi.com
Deinococcus radiodurans (D. radiodurans) can tolerate various extreme environments
including radiation. Protein phosphorylation plays an important role in radiation resistance …

DNA damage response and cell cycle regulation in bacteria: a twist around the paradigm

HS Misra, YS Rajpurohit - Frontiers in Microbiology, 2024 - frontiersin.org
The co-protease activity in the RecA-ssDNA complex cleaves the autorepressor LexA,
resulting in the derepression of a large number of genes under LexA control. This process is …

[HTML][HTML] Involvement of serine/threonine protein kinases in DNA damage response and cell division in bacteria

YS Rajpurohit, DK Sharma, HS Misra - Research in Microbiology, 2022 - Elsevier
Abstract The roles of Serine/Threonine protein kinases (STPKs) in bacterial physiology,
including bacterial responses to nutritional stresses and under pathogenesis have been well …

PprA Protein Inhibits DNA Strand Exchange and ATP Hydrolysis of Deinococcus RecA and Regulates the Recombination in Gamma-Irradiated Cells

YS Rajpurohit, DK Sharma, HS Misra - Frontiers in cell and …, 2021 - frontiersin.org
DrRecA and PprA proteins function are crucial for the extraordinary resistance to γ-radiation
and DNA strand break repair in Deinococcus radiodurans. DrRecA mediated homologous …

Surviving the storm: exploring the role of natural transformation in nutrition and DNA repair of stressed Deinococcus radiodurans

DK Sharma, I Soni, YS Rajpurohit - Applied and Environmental …, 2024 - journals.asm.org
Deinococcus radiodurans, a natural transformation (NT)-enabled bacterium renowned for its
exceptional radiation resistance, employs unique DNA repair and oxidative stress mitigation …

WD40 domain of RqkA regulates its kinase activity and role in extraordinary radioresistance of D. radiodurans

DK Sharma, SC Bihani, MQ Siddiqui… - Journal of …, 2022 - Taylor & Francis
RqkA, a DNA damage responsive serine/threonine kinase, is characterized for its role in
DNA repair and cell division in D. radiodurans. It has a unique combination of a kinase …

Single-Molecule Insights into ATP-Dependent Conformational Dynamics of Nucleoprotein Filaments of Deinococcus radiodurans RecA

A Alekseev, G Cherevatenko, M Serdakov… - International journal of …, 2020 - mdpi.com
Deinococcus radiodurans (Dr) has one of the most robust DNA repair systems, which is
capable of withstanding extreme doses of ionizing radiation and other sources of DNA …

Biochemical Characterization of RecO and RecR Proteins From Deinococcus radiodruans

K Jones - 2024 - search.proquest.com
Deinococcus radiodurans is an extraordinary bacterium for its ability to withstand a wide
variety of environmental stresses. One of its attributes is that D. radiodurans can withstand …