Ruthenium antimetastatic agents

E Alessio, G Mestroni, A Bergamo… - Current Topics in …, 2004 - ingentaconnect.com
NAMI-A, ie (imH)[trans-RuCl4 (dmso-S)(im)](im= imidazole, dmso= dimethylsulfoxide), is a
Ru (III) complex that, after extensive preclinical investigations that evidenced its remarkable …

Structure and bonding in metal sulfoxide complexes: an update

M Calligaris - Coordination chemistry reviews, 2004 - Elsevier
Average S O bond distances were calculated, from accurate X-ray data, for free and
coordinated sulfoxides, showing a decrease from free sulfoxides (avearge 1.492 (1) Å) to S …

Synthesis and reactivity of Ru-, Os-, Rh-, and Ir-halide− sulfoxide complexes

E Alessio - Chemical reviews, 2004 - ACS Publications
Platinum-group metal halide-sulfoxide complexes, and dimethyl sulfoxide (dmso) complexes
in particular, have a rich chemistry and are widely used as precursors in inorganic synthesis …

Ruthenium anticancer drugs

E Alessio, G Mestroni, A Bergamo… - Metal ions in biological …, 2004 - api.taylorfrancis.com
Several ruthenium-based compounds have been proven to posses interesting biological
properties that can lead to innovative drugs, particularly in the field of cancer treatment [1 5] …

Synthesis, antitumor activity and structure–activity relationships of a series of Ru (II) complexes

J Liu, W Zheng, S Shi, C Tan, J Chen, K Zheng… - Journal of inorganic …, 2008 - Elsevier
A series of octahedral Ru (II) polypyridyl complexes,[Ru (phen) 2L] 2+(L= R-PIP and PIP= 2-
phenylimidazo [4, 5-f][1, 10] phenanthroline) were synthesized and characterized by …

Inverse coordination. Organic nitrogen heterocycles as coordination centers. A survey of molecular topologies and systematization. Part 2. Six-membered rings

I Haiduc - Journal of Coordination Chemistry, 2019 - Taylor & Francis
The review is a follow-up of a previous article (I. Haiduc, J. Coord. Chem.(2019). DOI:
10.1080/00958972.2019. 1641702), which introduced structures with five-membered …

Synthesis, characterization, and in vitro evaluation of a potentially selective anticancer, mixed-metal [ruthenium (III)− platinum (II)] trinuclear complex

A Herman, JM Tanski, MF Tibbetts… - Inorganic …, 2008 - ACS Publications
A new type of mixed-metal trinuclear complex containing platinum (II) and ruthenium (III)
fragments that resemble both cisplatin and NAMI-A has been synthesized and characterized …

[PDF][PDF] 金属钌配合物的抗肿瘤活性及其作用机理

刘杰, 计亮年, 梅文杰 - 化学进展, 2004 - manu56.magtech.com.cn
金属钌配合物的抗肿瘤活性及其作用机理3 Page 1 金属钌配合物的抗肿瘤活性及其作用机理3 刘
杰3 3 计亮年 (中山大学化学与化学工程学院基因工程教育部重点实验室广州510275) 梅文杰 …

Reduction of in vivo lung metastases by dinuclear ruthenium complexes is coupled to inhibition of in vitro tumour invasion

A Bergamo, G Stocco, C Casarsa… - International …, 2004 - spandidos-publications.com
Mononuclear ruthenium-dmso compounds showed interesting antimetastatic properties on
experimental models of solid tumours. In line with the interesting results with multinuclear …

RNA binding and inhibition of primer extension by a Ru (III)/Pt (II) metal complex

SS Jain, CM Anderson, F DiRienzo, IR Taylor… - Chemical …, 2013 - pubs.rsc.org
AH197, a trinuclear Ru (III)/Pt (II) metal complex, is strikingly more effective than the hallmark
anticancer drug cisplatin and the Ru (III) clinical candidate NAMI-A in its binding to RNA and …