Sepsis is an unusual systemic reaction to what is sometimes an otherwise ordinary infection,
and it probably represents a pattern of response by the immune system to injury. A hyper …

Sepsis is among the most common causes of death in hospitals. It arises from the host
response to infection. Currently, diagnosis relies on nonspecific physiological criteria and …

Prognostic characteristics inform risk stratification in intensive care unit (ICU) patients with
coronavirus disease 2019 (COVID-19). We obtained blood samples (n= 474) from …

Background This study investigated the clinical value of interleukin-6 (IL-6), pentraxin 3
(PTX3), and procalcitonin (PCT) in patients with sepsis and septic shock diagnosed …

Abstract Long pentraxin 3 (PTX3) is an essential component of humoral innate immunity,
involved in resistance to selected pathogens and in the regulation of inflammation,–. The …

The first line of defense in innate immunity is provided by cellular and humoral mediators.
Pentraxins are a superfamily of phylogenetically conserved humoral mediators of innate …

The innate immune system constitutes the first line of defence against microorganisms and
plays a primordial role in the activation and regulation of adaptive immunity. The innate …

Humoral fluid phase pattern recognition molecules (PRM s) are a key component of the
activation and regulation of innate immunity. Humoral PRM s are diverse. We focused on the …

C‐reactive protein (CRP) is a pentraxin that has long been employed as a marker of
inflammation in clinical practice. Recent findings brought up the idea of CRP to be not only a …

Numerous studies have recently examined the role of pentraxin 3 (PTX3) in clinical
situations. The pentraxin family includes C‐reactive protein (CRP); however, unlike CRP …