Majority of the human genome is transcribed to RNAs that do not encode proteins. These
non-coding RNAs (ncRNAs) play crucial roles in regulating the initiation and progression of …

Abstract N6-methyladenosine (m6A) methylation, one of the most common RNA
modifications, has been reported to execute important functions that affect normal life …

LncRNA–miRNA interactions contribute to the regulation of therapeutic targets and
diagnostic biomarkers in multifarious human diseases. However, it remains difficult to …

Chemoresistance of cancer cells is a major problem in treating cancer. Knowledge of how
cancer cells may die or resist cancer drugs is critical to providing certain strategies to …

Abstract N6-methyladenosine (m6A) is the most abundant mRNA modification. With the
development of antibody-based sequencing technologies and the findings of m6A-related …

After the initial investigations into applications of mesenchymal stem cells (MSCs) for cell
therapy, there was increased interest in their secreted soluble factors. Following studies of …

N 6-Methyladenosine (m 6 A) is a prevalent modification present in the mRNAs of higher
eukaryotes. YTH domain family 2 (YTHDF2), an m 6 A" reader" protein, can recognize …

The pluripotency-associated transcription factor SOX2 is essential during mammalian
embryogenesis and later in life, but SOX2 expression can also be highly detrimental. Over …

There is growing evidence that regions of the genome that cannot encode proteins play an
important role in diseases. These regions are usually transcribed into long non-coding …

Activated microglia cells (MCs) are able to release a large amount of inflammatory cytokines
after ischemic stroke, which exacerbates neuron damage. In this study, we explored the …