Hypertension is a frequent condition encountered during kidney disease development and a
leading cause in its progression. Hallmark factors contributing to hypertension constitute a …

The cellular mechanisms and signaling network that guide the cardiac disease
pathophysiology are inextricably intertwined, which explains the current scarcity of effective …

Aims We explored the relationship between inflammation, renalase an anti-inflammatory
protein, and acute chest pain with coronary microvascular dysfunction (CMD). Methods and …

Aims Renalase, an enzyme that can metabolize catecholamine, was recently reported to
attenuate the ischaemia/reperfusion (I/R)-induced cardiac injury. This work was undertaken …

Background/Aims: Renalase, a novel flavoprotein expressed in the kidney and heart,
reduces renal tubular necrosis and apoptosis, which suggests that it might protect against …

Background Repeated administration of cisplatin causes CKD. In previous studies, we
reported that the kidney-secreted survival protein renalase (RNLS) and an agonist peptide …

Renalase, a recently discovered flavoprotein, which is strongly expressed in the kidney and
heart, effectively metabolizes catecholamines. It was discovered during the search to identify …

AKI is characterized by increased catecholamine levels and hypertension. Renalase, a
secretory flavoprotein that oxidizes catecholamines, attenuates ischemic injury and the …

Objectives: Describe the four clinical phases of acute tubular necrosis. Explain how to
evaluate a patient for acute tubular necrosis. Explain how to manage a patient with acute …

Background An increased risk for developing essential hypertension, stroke and diabetes is
associated with single nucleotide gene polymorphisms in renalase, a newly described …