Fluorescent multifunctional organic nanoparticles for drug delivery and bioimaging: a tutorial review

G Vargas-Nadal, M Köber, A Nsamela, F Terenziani… - Pharmaceutics, 2022 - mdpi.com
Fluorescent organic nanoparticles (FONs) are a large family of nanostructures constituted by
organic components that emit light in different spectral regions upon excitation, due to the …

The secret lives of fluorescent membrane probes as revealed by molecular dynamics simulations

HAL Filipe, MJ Moreno, LMS Loura - Molecules, 2020 - mdpi.com
Fluorescent probes have been employed for more than half a century to study the structure
and dynamics of model and biological membranes, using spectroscopic and/or microscopic …

Benchmarking density functional approximations for excited-state properties of fluorescent dyes

AM Grabarz, B Ośmiałowski - Molecules, 2021 - mdpi.com
This study presents an extensive analysis of the predictive power of time-dependent density
functional theory in determining the excited-state properties of two groups of important …

Unravelling the effects of cholesterol on the second-order nonlinear optical responses of Di-8-ANEPPS dye embedded in phosphatidylcholine lipid bilayers

C Bouquiaux, F Castet… - The Journal of Physical …, 2021 - ACS Publications
Cholesterol is known for its role in maintaining the correct fluidity and rigidity of the animals
cell membranes and thus their functions. Assessing the content and the role of cholesterol in …

Second-order nonlinear optical properties of an amphiphilic dye embedded in a lipid bilayer. A combined molecular dynamics–quantum chemistry study

C Bouquiaux, C Tonnelé, F Castet… - The Journal of …, 2020 - ACS Publications
The second harmonic signal of an amphiphilic dye embedded in a lipid bilayer has been
calculated by combining molecular dynamics simulations and quantum chemistry …

[HTML][HTML] Generalized polarization and time-resolved fluorescence provide evidence for different populations of Laurdan in lipid vesicles

M Bacalum, M Radu, S Osella, S Knippenberg… - … of Photochemistry and …, 2024 - Elsevier
The solvatochromic dye Laurdan is widely used in sensing the lipid packing of both model
and biological membranes. The fluorescence emission maximum shifts from about 440 nm …

First hyperpolarizability of water at the air–vapor interface: a QM/MM study questions standard experimental approximations

G Le Breton, O Bonhomme, PF Brevet… - Physical Chemistry …, 2021 - pubs.rsc.org
Surface Second-Harmonic Generation (S-SHG) experiments provide a unique approach to
probe interfaces. One important issue for S-SHG is how to interpret the S-SHG intensities at …

Photophysics in Biomembranes: Computational Insight into the Interaction between Lipid Bilayers and Chromophores

S Osella, S Knippenberg - Accounts of Chemical Research, 2024 - ACS Publications
Conspectus Light is ubiquitously available to probe the structure and dynamics of
biomolecules and biological tissues. Generally, this cannot be done directly with visible light …

Probing the Origins of the Disorder-to-Order Transition of a Modified Cholesterol in Ternary Lipid Bilayers

A Majumder, Y Gu, YC Chen, X An… - Journal of the …, 2024 - ACS Publications
In a recent study, spectroscopic observations of modified cholesterol in both lipid-coated
nanoparticles and liposomes provided evidence for a disorder-to-order orientational …

Conformational changes as driving force for phase recognition: The case of Laurdan

S Osella, N Smisdom, M Ameloot, S Knippenberg - Langmuir, 2019 - ACS Publications
The development of a universal probe to assess the phase of a lipid membrane is one of the
most ambitious goals for fluorescence spectroscopy. The ability of a well-known molecule as …