Update on gastric cancer treatments and gene therapies

A Biagioni, I Skalamera, S Peri, N Schiavone… - Cancer and Metastasis …, 2019 - Springer
Gastric cancer is an active topic of clinical and basic research due to high morbidity and
mortality. To date, gastrectomy and chemotherapy are the only therapeutic options for gastric …

Aberrant methylation patterns in cancer: a clinical view

A Videtic Paska, P Hudler - Biochemia medica, 2015 - hrcak.srce.hr
Sažetak Epigenetic mechanisms, such as DNA methylation, DNA hydroxymethylation, post-
translational modifications (PTMs) of histone proteins affecting nucleosome remodelling …

Aberrant expression of UCA1 in gastric cancer and its clinical significance

Q Zheng, F Wu, WY Dai, DC Zheng, C Zheng… - Clinical and …, 2015 - Springer
Long noncoding RNAs (lncRNAs) have been shown to regulate tumor biology and might be
used for cancer diagnosis, prognosis and potential therapeutic targets. Although up …

Novel prognostic biomarkers of gastric cancer based on gene expression microarray: COL12A1, GSTA3, FGA and FGG

S Duan, B Gong, P Wang… - Molecular …, 2018 - spandidos-publications.com
Gastric cancer (GC) is the fifth most common malignancy and the third leading cause of
cancer‑associated mortality in the world. However, its mechanisms of occurrence and …

[HTML][HTML] Challenges of deciphering gastric cancer heterogeneity

P Hudler - World Journal of Gastroenterology: WJG, 2015 - ncbi.nlm.nih.gov
Gastric cancer is in decline in most developed countries; however, it still accounts for a
notable fraction of global mortality and morbidity related to cancer. High-throughput methods …

Gastric cancer and imaging biomarkers: Part 1–a critical review of DW-MRI and CE-MDCT findings

F Giganti, L Tang, H Baba - European radiology, 2019 - Springer
The current standard of care for gastric cancer imaging includes heterogeneity in image
acquisition techniques and qualitative image interpretation. In addition to qualitative …

Advances in prognostic biomarkers for esophageal cancer

W Yang, Y Han, X Zhao, L Duan, W Zhou… - Expert review of …, 2019 - Taylor & Francis
Introduction: Esophageal cancer (EC) is one of the deadliest neoplasms in Asian countries.
The high mortality rate and low survival rate of this disease are the major challenges for …

Whole mitochondrial genome sequencing highlights mitochondrial impact in gastric cancer

GC Cavalcante, ANR Marinho, AK Anaissi… - Scientific reports, 2019 - nature.com
Mitochondria are organelles that perform major roles in cellular operation. Thus, alterations
in mitochondrial genome (mtGenome) may lead to mitochondrial dysfunction and cellular …

3, 3'-Diindolylmethane potentiates paclitaxel-induced antitumor effects on gastric cancer cells through the Akt/FOXM1 signaling cascade

H Jin, MH Park, SM Kim - Oncology reports, 2015 - spandidos-publications.com
Gastric cancer is the fourth most common cancer and is one of the leading causes of cancer-
related mortality worldwide. Forkhead box M1 (FOXM1) is overexpressed in gastric cancer …

[HTML][HTML] Long noncoding RNAs as auxiliary biomarkers for gastric cancer screening: a pooled analysis of individual studies

Z Cui, Y Chen, Z Xiao, M Hu, Y Lin, Y Chen, Y Zheng - Oncotarget, 2016 - ncbi.nlm.nih.gov
Background Long non-coding RNAs (lncRNAs) are highlighted as novel cancer biomarkers
with great promise. Herein, we focused on summarizing the overall diagnostic performance …