Endothelial dysfunction in COVID-19: an overview of evidence, biomarkers, mechanisms and potential therapies
The fight against coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is
still raging. However, the pathophysiology of acute and post-acute manifestations of COVID …
still raging. However, the pathophysiology of acute and post-acute manifestations of COVID …
Post-acute sequelae of COVID-19: A metabolic perspective
The SARS-CoV-2 pandemic continues to rage around the world. At the same time, despite
strong public health measures and high vaccination rates in some countries, a post-COVID …
strong public health measures and high vaccination rates in some countries, a post-COVID …
COVID-19 and the vasculature: current aspects and long-term consequences
B Martinez-Salazar, M Holwerda, C Stuedle… - Frontiers in cell and …, 2022 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) was first identified in
December 2019 as a novel respiratory pathogen and is the causative agent of Corona Virus …
December 2019 as a novel respiratory pathogen and is the causative agent of Corona Virus …
Integrin mediates cell entry of the SARS-CoV-2 virus independent of cellular receptor ACE2
Coronavirus disease 2019 (COVID-19) is a highly contagious disease caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It is broadly accepted that SARS …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It is broadly accepted that SARS …
The fatal trajectory of pulmonary COVID-19 is driven by lobular ischemia and fibrotic remodelling
M Ackermann, JC Kamp, C Werlein, CL Walsh… - …, 2022 - thelancet.com
Background COVID-19 is characterized by a heterogeneous clinical presentation, ranging
from mild symptoms to severe courses of disease. 9–20% of hospitalized patients with …
from mild symptoms to severe courses of disease. 9–20% of hospitalized patients with …
Identification of host transcriptome-guided repurposable drugs for SARS-CoV-1 infections and their validation with SARS-CoV-2 infections by using the integrated …
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is one of the most severe
global pandemic due to its high pathogenicity and death rate starting from the end of 2019 …
global pandemic due to its high pathogenicity and death rate starting from the end of 2019 …
SARS-CoV-2 Infects Human ACE2-Negative Endothelial Cells through an αvβ3 Integrin-Mediated Endocytosis Even in the Presence of Vaccine-Elicited Neutralizing …
A Bugatti, F Filippini, M Bardelli, A Zani, P Chiodelli… - Viruses, 2022 - mdpi.com
Integrins represent a gateway of entry for many viruses and the Arg-Gly-Asp (RGD) motif is
the smallest sequence necessary for proteins to bind integrins. All Severe Acute Respiratory …
the smallest sequence necessary for proteins to bind integrins. All Severe Acute Respiratory …
Altered lipid profile in COVID-19 patients and metabolic reprogramming
T Zhao, C Wang, B Duan, P Yang, J Wu… - Frontiers in …, 2022 - frontiersin.org
Background Coronavirus disease 2019 (COVID-19) is a global pandemic. Previous studies
have reported dyslipidemia in patients with COVID-19. Herein, we conducted a retrospective …
have reported dyslipidemia in patients with COVID-19. Herein, we conducted a retrospective …
[HTML][HTML] An innovative strategy to investigate microbial protein modifications in a reliable fast and sensitive way: A therapy oriented proof of concept based on UV-C …
The characterization of modifications of microbial proteins is of primary importance to dissect
pathogen lifecycle mechanisms and could be useful in identifying therapeutic targets …
pathogen lifecycle mechanisms and could be useful in identifying therapeutic targets …
Competition for dominance within replicating quasispecies during prolonged SARS-CoV-2 infection in an immunocompromised host
F Caccuri, S Messali, D Bortolotti, D Di Silvestre… - Virus …, 2022 - academic.oup.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs)
emerge for their capability to better adapt to the human host aimed and enhance human-to …
emerge for their capability to better adapt to the human host aimed and enhance human-to …