Preterm birth (PTB) is the leading cause of childhood mortality in children under 5 and
accounts for approximately 11% of births worldwide. Premature babies are at risk of a …

Acute chorioamnionitis is characterized by neutrophilic infiltration and inflammation at the
maternal fetal interface. It is a relatively common complication of pregnancy and can have …

Background Brain growth and structural organization occurs in stages beginning prenatally.
Toxicants may impact neurodevelopment differently dependent upon exposure timing and …

Zika virus (ZIKV) crosses the placenta and causes congenital disease. Here we develop an
animal model utilizing direct ZIKV inoculation into the uterine wall of pregnant …

Dysbiosis of the gut microbiome in preterm infants predisposes the neonate to various major
morbidities including neonatal necrotizing enterocolitis and sepsis in the neonatal intensive …

Background Prenatal exposure to air pollutants including particulate matter (< 2.5 μm of
diameter, PM 2.5) and nitrogen dioxide (NO 2) has been identified as a potential risk factor …

Neurodegeneration represents a global problem due to the progressive increase in the
aging population all over the world. The quality of life in aging and the cost for the health …

Autism spectrum disorder (ASD) is a highly complex and heterogeneous developmental
disorder that affects how individuals communicate with other people and relate to the world …

Neonatal period is the most vulnerable time for the occurrence of seizures, and neonatal
seizures often pose a clinical challenge both for their acute management and frequency of …

Human umbilical cord mesenchymal stem cells (MSCs) have been reported to improve the
migration and invasion of trophoblast cells; however, little is known about whether MSC …