Cardiovascular diseases (CVD)(such as occlusion of the coronary arteries, hypertensive
heart diseases and strokes) are diseases that generate thousands of patients with a high …

Oxidative stress plays a significant role in the pathogenesis of cardiovascular diseases, such
as myocardial ischemia/reperfusion injury, atherosclerosis, heart failure, and hypertension …

When faced with increased workload the heart undergoes remodelling, where it increases
its muscle mass in an attempt to preserve normal function. This is referred to as cardiac …

Medical advances and the availability of diagnostic tools have considerably increased life
expectancy and, consequently, the elderly segment of the world population. As age is a …

Lipids can go through lipid peroxidation, an endogenous chain reaction that consists in the
oxidative degradation of lipids leading to the generation of a wide variety of highly reactive …

It is now well known that oxidative stress promotes lipid peroxidation, protein oxidation,
activation of proteases, fragmentation of DNA and alteration in gene expression for …

We compared the influence of aerobic and resistance exercise on cardiac remodelling,
physical capacity and skeletal muscle oxidative stress in rats with MI‐induced heart failure …

Although well documented drug therapies are available for the management of ventricular
hypertrophy (VH) and heart failure (HF), most patients nonetheless experience a downhill …

Pompe disease is a metabolic myopathy due to acid alpha‐glucosidase deficiency. In
addition to glycogen storage, secondary dysregulation of cellular functions, such as …

MYBPC3, encoding cardiac myosin binding protein-C (cMyBP-C), is the most mutated gene
known to cause hypertrophic cardiomyopathy (HCM). However, since little is known about …