[HTML][HTML] Mycobacteriophages in diagnosis and alternative treatment of mycobacterial infections

X Ouyang, X Li, J Song, H Wang, S Wang… - Frontiers in …, 2023 - frontiersin.org
Antimicrobial resistance is an increasing threat to human populations. The emergence of
multidrug-resistant “superbugs” in mycobacterial infections has further complicated the …

[HTML][HTML] Bacteriophage therapy and current delivery strategies for orthopedic infections: A SCOPING review

J Young, SW Lee, MJ Shariyate, A Cronin, JJ Wixted… - Journal of Infection, 2024 - Elsevier
Objectives Interest in phages as adjunctive therapy to treat difficult infections has grown in
the last decade. However, phage dosing and delivery for orthopedic infections have not …

Synergy of lytic phage pB23 and meropenem combination against carbapenem-resistant Acinetobacter baumannii

J Luo, M Liu, W Ai, X Zheng, S Liu… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
Phage-antibiotic combination treatment is a novel noteworthy drug delivery method in anti-
infection. In the current study, we have isolated a new phage, pB23, against carbapenem …

[HTML][HTML] Response surface methodology application for bacteriophage–antibiotic Antibiofilm activity optimization

B Grygorcewicz, M Gliźniewicz, P Olszewska, D Miłek… - Microorganisms, 2023 - mdpi.com
Phage–antibiotic combination-based protocols are presently under heightened
investigation. This paradigm extends to engagements with bacterial biofilms, necessitating …

Synergistic bactericidal effects of phage-enhanced antibiotic therapy against MRSA biofilms

AJ Kunz Coyne, K Stamper, C Bleick… - Microbiology …, 2024 - Am Soc Microbiol
Methicillin-resistant Staphylococcus aureus (MRSA) causes biofilm-related medical device
infections. Phage-antibiotic combinations offer potential therapy due to proven in vitro …

[HTML][HTML] Automating Predictive Phage Therapy Pharmacology

ST Abedon - Antibiotics, 2023 - mdpi.com
Viruses that infect as well as often kill bacteria are called bacteriophages, or phages.
Because of their ability to act bactericidally, phages increasingly are being employed …

Phage Therapy for Respiratory Infections: Opportunities and Challenges

A Khosravi, Q Chen, A Echterhof, JL Koff, PL Bollyky - Lung, 2024 - Springer
We are entering the post-antibiotic era. Antimicrobial resistance (AMR) is a critical problem
in chronic lung infections resulting in progressive respiratory failure and increased mortality …

Phage-antibiotic synergy against daptomycin-nonsusceptible MRSA in an ex vivo simulated endocardial pharmacokinetic/pharmacodynamic model

AJ Kunz Coyne, C Bleick, K Stamper… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
Phage-antibiotic combinations (PAC) offer a potential solution for treating refractory
daptomycin-nonsusceptible (DNS) methicillin-resistant Staphylococcus aureus (MRSA) …

[HTML][HTML] Comparison of Antibiofilm Activity of Pseudomonas aeruginosa Phages on Isolates from Wounds of Diabetic and Non-Diabetic Patients

S Suresh, J Saldanha, A Bhaskar Shetty, R Premanath… - Microorganisms, 2023 - mdpi.com
The persistence of organisms as biofilms and the increase in antimicrobial resistance has
raised the need for alternative strategies. The study objective was to compare the ability of …

[HTML][HTML] The Antibacterial Activity of Novel Bacteriophages and the Emergence of Bacterial Resistance to Phage Infections: An In Vitro Study

LS Moda-Silva, VC Oliveira, TA da Cruz… - Applied …, 2024 - mdpi.com
The emergence of bacteria resistant to bacteriophage (phage) infection may compromise
the success and effectiveness of phage therapy. The aim of this study was to evaluate the in …