Epidemiology and immune pathogenesis of viral sepsis

GL Lin, JP McGinley, SB Drysdale… - Frontiers in …, 2018 - frontiersin.org
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to
infection. Sepsis can be caused by a broad range of pathogens; however, bacterial …

Prevalence of post-traumatic stress disorder symptoms in adult critical care survivors: a systematic review and meta-analysis

C Righy, RG Rosa, RTA da Silva, R Kochhann… - Critical care, 2019 - Springer
Background As more patients are surviving intensive care, mental health concerns in
survivors have become a research priority. Among these, post-traumatic stress disorder …

The “centrality of sepsis”: a review on incidence, mortality, and cost of care

J Hajj, N Blaine, J Salavaci, D Jacoby - Healthcare, 2018 - mdpi.com
Sepsis is a serious and fatal medical condition that has overburdened the US healthcare
system. The purpose of this paper is to provide a review of published literature on severe …

Rate and risk factors for rehospitalisation in sepsis survivors: systematic review and meta-analysis

M Shankar-Hari, R Saha, J Wilson, HC Prescott… - Intensive care …, 2020 - Springer
Purpose Sepsis survivors have a higher risk of rehospitalisation and of long-term mortality.
We assessed the rate, diagnosis, and independent predictors for rehospitalisation in adult …

Cardiovascular events among survivors of sepsis hospitalization: a retrospective cohort analysis

JC Jentzer, PR Lawler, HK Van Houten… - Journal of the …, 2023 - Am Heart Assoc
Background Sepsis is associated with an elevated risk of late cardiovascular events among
hospital survivors. Methods and Results We included OptumLabs Data Warehouse patients …

Characterization of pathogenic sepsis etiologies and patient profiles: a novel approach to triage and treatment

HH Dolin, TJ Papadimos, X Chen… - Microbiology …, 2019 - journals.sagepub.com
Pathogenic sepsis is not a monolithic condition. Three major types of sepsis exist within this
category: bacterial, viral, and fungal, each with its own mechanism of action. While similar in …

Association between adherence to recommended care and outcomes for adult survivors of sepsis

SP Taylor, SH Chou, MF Sierra, TP Shuman… - Annals of the …, 2020 - atsjournals.org
Rationale: Postsepsis care recommendations target specific deficits experienced by sepsis
survivors in elements such as optimization of medications, screening for functional …

Vascular endothelial cadherin shedding is more severe in sepsis patients with severe acute kidney injury

WK Yu, JB McNeil, NE Wickersham, CM Shaver… - Critical Care, 2019 - Springer
Background Vascular endothelial cadherin (VE-cadherin) is a membrane protein that is the
major component of adherens junctions between endothelial cells. It is crucial for regulating …

Angiotensin II enhances bacterial clearance via myeloid signaling in a murine sepsis model

DE Leisman, JR Privratsky… - Proceedings of the …, 2022 - National Acad Sciences
Sepsis, defined as organ dysfunction caused by a dysregulated host-response to infection,
is characterized by immunosuppression. The vasopressor norepinephrine is widely used to …

The burden of mental illness among survivors of critical care—risk factors and impact on quality of life: a multicenter prospective cohort study

C Teixeira, RG Rosa, D Sganzerla, EC Sanchez… - Chest, 2021 - Elsevier
Background Survivors of critical care may demonstrate mental health disorders in the
months after discharge. Research Question What are risk factors for mental health disorders …